Kinase profiling results of kinases in KIF 1MP8A_ADP (PTK2, PDB code: 1MP8, chain A)
Template Kinase: PTK2
Template inhibitor: Adenosine-5'-diphosphate

 16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
AURKAOther
NEK2Other
PLK4Other
STK24STE
ALKTK
EGFRTK
PTK2TK
PTK2BTK
FGFR1TK
FGFR2TK
INSRTK
METTK
SRCTK
HCKTK
ZAP70TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CDK2CMGC
AURKAOther
NEK2Other
STK24STE
ALKTK
EGFRTK
FGFR1TK
FGFR2TK
HCKTK
INSRTK
METTK
PTK2TK
PTK2BTK
SRCTK
ZAP70TK