Kinase profiling results of kinases in KIF 3FZPA_AGS (PTK2B, PDB code: 3FZP, chain A)
Template Kinase: PTK2B
Template inhibitor: adenosine tetraphosphate

 17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AURKAOther
NEK2Other
EIF2AK2Other
ABL1TK
EGFRTK
ERBB3TK
EPHA2TK
EPHA3TK
PTK2TK
PTK2BTK
FGFR2TK
IGF1RTK
INSRTK
SRCTK
HCKTK
LCKTK
ZAP70TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AURKAOther
NEK2Other
ABL1TK
EGFRTK
EPHA2TK
EPHA3TK
FGFR2TK
HCKTK
IGF1RTK
INSRTK
LCKTK
PTK2TK
PTK2BTK
SRCTK
ZAP70TK