Kinase profiling results of kinases in KIF 2IVSA_ACK (RET, PDB code: 2IVS, chain A)
Template Kinase: RET
Template inhibitor: 5'-adenylic acid

 10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AURKAOther
STK24STE
ABL1TK
ALKTK
MERTKTK
PTK2TK
KITTK
RETTK
SRCTK
MAP3K7TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
AURKAOther 
STK24STE 
ABL1TK 
ALKTK 
KITTK 
MERTKTK 
PTK2TK 
RETTK 
SRCTK 
MAP3K7TKL