Kinase profiling results of kinases in KIF 2X2LA_X2L (RET, PDB code: 2X2L, chain A)
Template Kinase: RET
Template inhibitor: DNC010329

2 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PTK2TK
RETTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
PTK2TK  
RETTK