Kinase profiling results of kinases in KIF 2R3HA_SCE (CDK2, PDB code: 2R3H, chain A)
Template Kinase: CDK2
Template inhibitor: benzimidazoquinoxaline analogue, 7a

15 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
ROCK2AGC 
PIM1CAMK 
CDK2CMGC 
CDK4CMGC 
CSNK2A1CMGC 
GSK3BCMGC 
MAPK14CMGC 
AURKBOther 
CHUKOther 
PLK1Other 
ABL1TK 
JAK2TK 
SRCTK 
LCKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
AKT1AGC  
ROCK2AGC  
PIM1CAMK  
CDK2CMGC  
CDK4CMGC  
CSNK2A1CMGC  
GSK3BCMGC  
MAPK14CMGC  
AURKBOther  
CHUKOther  
PLK1Other  
ABL1TK  
JAK2TK  
LCKTK  
SRCTK