Kinase profiling results of kinases in KIF 2X7GA_PVB (SRPK2, PDB code: 2X7G, chain A)
Template Kinase: SRPK2
Template inhibitor: Purvalanol B

3 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
DYRK1BCMGC
SRPK2CMGC
SRPK3CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
DYRK1BCMGC     
SRPK2CMGC     
SRPK3CMGC