Kinase profiling results of kinases in KIF 2WTKC_ANP (STK11, PDB code: 2WTK, chain C)
Template Kinase: STK11
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
PRKCIAGC
STK11CAMK
MAPKAPK23
CHEK2CAMK
GSK3BCMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
PDPK1AGC
PRKCIAGC
CHEK2CAMK
MAPKAPK2CAMK
STK11CAMK
GSK3BCMGC