Kinase profiling results of kinases in KIF 3L8PA_0CE (TEK, PDB code: 3L8P, chain A)
Template Kinase: TEK
Template inhibitor: LY_333531

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
PRKCQAGC 
ITKTK 
TEKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKCQAGC 
CDK6CMGC 
CDK6CMGC 
ITKTK 
TEKTK