Kinase profiling results of kinases in KIF 3GXLA_QIG (TGFBR1, PDB code: 3GXL, chain A)
Template Kinase: TGFBR1
Template inhibitor: DB08450

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ABL1TK 
ABL2TK 
FYNTK 
SRCTK 
LCKTK 
BMXTK 
TGFBR1TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
ABL1TK   
ABL2TK   
BMXTK   
FYNTK   
LCKTK   
SRCTK   
TGFBR1TKL