Kinase profiling results of kinases in KIF 3HMNA_ATP (TTK, PDB code: 3HMN, chain A)
Template Kinase: TTK
Template inhibitor: Adenosine-5'-triphosphate

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
RPS6KA1AGC
RPS6KA1CAMK
DAPK1CAMK
PIM1CAMK
CDK2CMGC
NEK2Other
TTKOther
STK24STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PDPK1AGC
RPS6KA1AGC
DAPK1CAMK
PIM1CAMK
CDK2CMGC
NEK2Other
TTKOther
STK24STE