Kinase profiling results of kinases in KIF 3NYXA_TZ1 (TYK2, PDB code: 3NYX, chain A)
Template Kinase: TYK2
Template inhibitor: AC1MOHSZ

 3 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ABL1TK
TYK2TK
SRCTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
ABL1TK
SRCTK
TYK2TK