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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Summary of query kinase
Query kinase
NEK4 (
P51957
)
Kinase group
Other
Number of conformation types
0
Number of structural templates
28 (
Total 12 inhibitors
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
17
1SM2A_STU
(ITK)
Other
staurosporine
I
99
104
128
A
1SM2A_STU
(ITK)
Other
staurosporine
I
99
104
128
99
104
128
A
3HMOA_STU
(TTK)
Other
staurosporine
I
27
50
20
27
50
20
A
1SNUA_STU
(ITK)
Other
staurosporine
I
99
104
128
99
104
128
A
1AQ1A_STU
(CDK2)
Other
staurosporine
I
195
76
118
195
76
118
A
2HZ4A_4ST
(ABL1)
Other
staurosporine
I
159
103
156
159
103
156
A
1NVRA_STU
(CHEK1)
Other
staurosporine
I
179
71
79
179
71
79
A
1NXKA_STU
(MAPKAPK2)
Other
staurosporine
I
110
67
51
110
67
51
A
1QPDA_STU
(LCK)
Other
staurosporine
I
115
76
126
115
76
126
A
1QPJA_STU
(LCK)
Other
staurosporine
I
115
76
126
115
76
126
A
3L8XA_N4D
(MAPK14)
Other
3cg2
I
91
104
65
91
104
65
A
1NVSA_UCM
(CHEK1)
Other
SB218078
I
97
6
53
97
6
53
A
3PJ3A_04L
(BTK)
Other
Imatinib
II
99
113
134
99
113
134
A
2IW6A_QQ2
(CDK2)
Other
2iw6
I
112
209
86
112
209
86
A
3PIYA_585
(BTK)
Other
R-406
I
93
17
123
93
17
123
A
3GFWA_S22
(TTK)
Other
1-(4-(4-(2-(...
I
21
4
18
21
4
18
A
1NVQA_UCN
(CHEK1)
Other
UCN 02
I
179
65
79
179
65
79
A
1PKDA_UCN
(CDK2)
Other
UCN 02
I
195
67
118
195
67
118
B
11
3BKBA_STU
(FES)
Other
staurosporine
I
131
107
138
B
3BKBA_STU
(FES)
Other
staurosporine
I
131
107
138
131
107
138
B
3CBLA_STU
(FES)
Other
staurosporine
I
131
107
138
131
107
138
B
1OKYA_STU
(PDPK1)
Other
staurosporine
I
179
67
109
179
67
109
B
3CD3A_STU
(FES)
Other
staurosporine
I
131
107
138
131
107
138
B
3D7TA_STU
(CSK)
Other
staurosporine
I
70
68
99
70
68
99
B
3EFWA_AK8
(AURKA)
Other
3efw
I
100
59
105
100
59
105
B
1H07A_MFP
(CDK2)
Other
AC1NAKJQ
I
90
241
80
90
241
80
B
2VWUA_7X1
(EPHB4)
Other
Chlorobenzod...
I
77
287
111
77
287
111
B
3F5PA_741
(IGF1R)
Other
3-cyanoquino...
I
60
123
81
60
123
81
B
3COHA_83H
(AURKA)
Other
AKI-001
I
79
88
65
79
88
65
B
1OKZA_UCN
(PDPK1)
Other
UCN 02
I
179
60
109
179
60
109