Allelic Variants

There are no related allelic variants
Related diseases of KIF 1AQ1A_STU (PDB code: 1AQ1, chain A)
Number of involved diseases in the family 118
Number of AKT3 related diseases 11
All kinase in this family  AKT3
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
n/aEpstein-Barr virus infectionAKT1, AKT2, AKT3, CDC2,
CDK2, CHUK, CSNK2A1,
CSNK2A2, EIF2AK2, FGR,
GSK3B, JAK1, JAK3, LYN,
MAP2K3, MAP2K6, MAP3K7,
MAPK10, MAPK12, MAPK13,
MAPK14, MAPK8, MAPK9		21Link
n/aInfluenza AAKT1, AKT2, AKT3, EIF2AK2,
GSK3B, IRAK4, JAK1, JAK2,
MAP2K1, MAP2K3, MAP2K6,
MAPK1, MAPK10, MAPK12,
MAPK13, MAPK14, MAPK8,
MAPK9, PRKCA, PRKCB		62Link
n/aMeaslesAKT1, AKT2, AKT3, CDK2,
CDK4, CDK6, CHUK, CSNK2A1,
CSNK2A2, EIF2AK2, FYN,
GSK3B, IRAK4, JAK1, JAK2,
JAK3, MAP3K7, PRKCQ		19Link
n/aTuberculosisAKT1, AKT2, AKT3, CAMK2A,
CAMK2B, CAMK2D, IRAK4, JAK1,
JAK2, MAPK1, MAPK10, MAPK12,
MAPK13, MAPK14, MAPK8,
MAPK9, PLK3, SRC		22Link
n/aToxoplasmosisAKT1, AKT2, AKT3, CHUK,
IRAK4, JAK1, JAK2, MAP2K3,
MAP2K6, MAP3K7, MAPK1,
MAPK10, MAPK12, MAPK13,
MAPK14, MAPK8, MAPK9		14Link
LeukemiaABL1, ABL2, AKT1, AKT2,
AKT3, CDK4, CDK6, CHUK,
JAK2, MAP2K1, MAPK1, PIM1,
PIM2, RPS6KB1, RPS6KB2		15Link
n/aHepatitis CAKT1, AKT2, AKT3, CHUK,
EIF2AK2, GSK3B, JAK1, MAPK1,
MAPK10, MAPK12, MAPK13,
MAPK14, MAPK8, MAPK9		14Link
n/aHerpes simplex infectionCDC2, CDK2, CHUK, CSNK2A1,
CSNK2A2, EIF2AK2, JAK1,
JAK2, MAP3K7, MAPK10, MAPK8,
MAPK9		16Link
Prostate cancerAKT1, AKT2, AKT3, CDK2,
CHEK2, CHUK, FGFR1, FGFR2,
GSK3B, MAP2K1, MAPK1, PDPK1		17Link
n/aShigellosisABL1, CHUK, MAPK1, MAPK10,
MAPK12, MAPK13, MAPK14,
MAPK8, MAPK9, ROCK1, ROCK2,
SRC		22Link
n/aChagas diseaseAKT1, AKT2, AKT3, CHUK,
IRAK4, MAPK1, MAPK10,
MAPK12, MAPK13, MAPK14,
MAPK8, MAPK9		10Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCHUK, LYN, MAPK10, MAPK12,
MAPK13, MAPK14, MAPK8,
MAPK9, MET, PAK1, SRC		22Link
n/aSalmonella infectionMAPK1, MAPK10, MAPK12,
MAPK13, MAPK14, MAPK8,
MAPK9, PKN1, PKN2, ROCK1,
ROCK2		14Link
n/aLeishmaniasisIRAK4, JAK1, JAK2, MAP3K7,
MAPK1, MAPK12, MAPK13,
MAPK14, PRKCB		16Link
MelanomaAKT1, AKT2, AKT3, CDK4,
CDK6, FGFR1, MAP2K1, MAPK1,
MET		13Link
n/aPertussisIRAK4, MAPK1, MAPK10,
MAPK12, MAPK13, MAPK14,
MAPK8, MAPK9		10Link
Diabetes mellitusAKT2, MAPK1, MAPK10, MAPK8,
MAPK9, PRKCD, PRKCE		16Link
Lung cancerAKT1, AKT2, AKT3, CDK2,
CDK4, CDK6, CHUK		12Link
n/aAmyotrophic lateral sclerosisMAP2K3, MAP2K6, MAPK12,
MAPK13, MAPK14		11Link
n/aAlcoholismCAMKK1, CAMKK2, MAP2K1,
MAPK1, NTRK2		12Link
n/aPathogenic Escherichia coli infectionABL1, FYN, PRKCA, ROCK1,
ROCK2		61Link
Mental retardationCASK, DYRK1A, PAK3, RPS6KA311Link
n/aPrion diseasesFYN, MAP2K1, MAPK111Link
n/aViral myocarditisABL1, ABL2, FYN13Link
n/aImmunodeficienciesJAK3, LCK, ZAP7016Link
Colon cancerAURKA, SRC19Link
Crouzon syndromeFGFR2, FGFR38Link
Breast cancerAKT1, CHEK28Link
n/aEpileptic encephalopathyCDKL5, MAPK106Link
n/aEarly infantile epileptic encephalopathyCDKL5, MAPK106Link
n/aBasal cell carcinomaGSK3B, STK3610Link
Gastric cancerFGFR2, MET9Link
n/aCervical cancerCDK4, FGFR39Link
Ovarian cancerAKT1, AKT27Link
Colorectal cancerAKT1, FGFR37Link
n/aBladder cancerDAPK1, FGFR39Link
Pfeiffer syndromeFGFR1, FGFR29Link
Jackson-Weiss syndromeFGFR1, FGFR29Link
LADD syndromeFGFR2, FGFR38Link
NeuroblastomaNTRK2, NTRK39Link
SCIDJAK3, LCK16Link
n/aAfrican trypanosomiasisPRKCA, PRKCB55Link
n/aVibrio cholerae infectionPRKCA, PRKCB55Link
n/aNon-syndromic X-linked mental retardationPAK3, RPS6KA310Link
n/aAmoebiasisPRKCA, PRKCB55Link
n/aAutism suseptibilityMET8Link
n/aMaturity onset diabetes of the youngBLK8Link
n/aMalariaMET8Link
n/aCongenital myasthenic syndromeMUSK5Link
Hepatocellular carcinomaMET8Link
n/aFG syndromeCASK1Link
n/aMalignant melanomaCDK46Link
n/aMyasthenic syndromeMUSK5Link
Renal cell carcinomaMET8Link
Li-Fraumeni syndromeCHEK25Link
n/aAngelman syndrome-likeCDKL51Link
n/aCholangiocarcinomaMET8Link
n/aGliomaCDK46Link
n/aCocaine addictionCDK55Link
n/aPrader-Willi and Angelman syndromesCDKL51Link
n/aFamilial partial lipodystrophyAKT27Link
Hypoinsulinemic hypoglycemiaAKT27Link
n/aPituitary tumorPRKCA55Link
Glycogen storage diseasePHKG29Link
n/aCerebral infarctionPRKCH12Link
n/aPTEN hamartoma tumor syndromeAKT17Link
Selective T-cell defectZAP7010Link
n/aCoffin-Lowry syndromeRPS6KA38Link
n/aType I diabetes mellitusPRKCQ8Link
n/aCirrhosis due to liver phosphorylase kinase deficiencyPHKG29Link
n/aGlycogen storage diseasesPHKG29Link
OsteosarcomaCHEK25Link
n/aShort rib-polydactyly syndormeNEK13Link
n/aSchizophreniaAKT17Link
n/aProteus syndromeAKT17Link
n/aObesityNTRK29Link
n/aNephronophthisisNEK81Link
n/aNephronophthisis-medullary cystic kidney diseaseNEK81Link
Cardiofaciocutaneous syndromeMAP2K14Link
n/aInvasive pneumococcal diseaseIRAK44Link
n/aHypochondroplasiaFGFR37Link
n/aMuenke syndromeFGFR37Link
n/aNevusFGFR37Link
n/aAchondroplasiaFGFR37Link
n/aCATSHL syndromeFGFR37Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR28Link
n/aMultiple myelomaFGFR37Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR37Link
n/aSpermatocytic seminomaFGFR37Link
n/aThanatophoric dysplasiaFGFR37Link
n/aEndocrine-cerebroosteodysplasiaICK2Link
Lymphoproliferative syndromeITK6Link
IRAK4 deficiencyIRAK44Link
Polycythemia veraJAK210Link
n/aOguchi diseaseGRK14Link
n/aCancer progression/metastasisFGFR43Link
n/aBudd-Chiari syndromeJAK210Link
n/aCongenital stationary night blindnessGRK14Link
ScaphocephalyFGFR28Link
n/aSaethre-Chotzen syndromeFGFR28Link
Osteoglophonic dysplasiaFGFR19Link
TrigonocephalyFGFR19Link
REtinitis pigmentosaMAK1Link
Hypogonadotropic hypogonadismFGFR19Link
n/aSpondylometaepiphyseal dysplasiaDDR23Link
n/aCocoon syndromeCHUK6Link
n/aLegionellosisCLK18Link
n/aNoonan syndrome and related disordersMAP2K14Link
Kallmann syndromeFGFR19Link
ThrombocythemiaJAK210Link
CraniosynostosisFGFR28Link
n/aMyeloproliferative disorderJAK210Link
MyelofibrosisJAK210Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR28Link
Bent bone dysplasia syndromeFGFR28Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR28Link
Apert syndromeFGFR28Link
Beare-Stevenson cutis gyrata syndromeFGFR28Link