Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
94 |
Number of BLK related diseases |
1 |
All kinase in this family
BLK
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
| Prostate cancer | BRAF, CDK2, EGFR, ERBB2, FGFR1, IGF1R, PDGFRA, PDGFRB, RAF1 | 35 | Link | n/a | Epstein-Barr virus infection | CDC2, CDK2, FGR, IRAK1, JAK3, LYN, MAPK14, SYK, TYK2 | 55 | Link | | Leukemia | ABL1, ABL2, BRAF, JAK2, KIT, PDGFRB, RAF1, TGFBR1 | 75 | Link | | Melanoma | BRAF, EGFR, FGFR1, IGF1R, PDGFRA, PDGFRB, RAF1 | 31 | Link | n/a | Measles | CDK2, FYN, IRAK1, JAK2, JAK3, PRKCQ, TYK2 | 22 | Link | n/a | Tuberculosis | IRAK1, JAK2, MAPK14, RAF1, SRC, SYK | 68 | Link | n/a | Hepatitis C | BRAF, EGFR, MAPK14, RAF1, TYK2 | 25 | Link | n/a | Influenza A | JAK2, MAPK14, PRKCA, RAF1, TYK2 | 44 | Link | n/a | Toxoplasmosis | IRAK1, JAK2, MAPK14, TYK2 | 34 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | EGFR, LYN, MAPK14, SRC | 62 | Link | n/a | Herpes simplex infection | CDC2, CDK2, JAK2, TYK2 | 17 | Link | n/a | Leishmaniasis | IRAK1, JAK2, MAPK14 | 34 | Link | n/a | Viral myocarditis | ABL1, ABL2, FYN | 50 | Link | n/a | Pathogenic Escherichia coli infection | ABL1, FYN, PRKCA | 52 | Link | n/a | Choriocarcinoma | CSF1R, EGFR, ERBB2 | 13 | Link | n/a | Glioma | EGFR, PDGFRA, PDGFRB | 26 | Link | n/a | Shigellosis | ABL1, MAPK14, SRC | 98 | Link | n/a | Thyroid cancer | BRAF, NTRK1, RET | 8 | Link | n/a | Chagas disease | IRAK1, MAPK14, TGFBR1 | 23 | Link | | Lung cancer | BRAF, CDK2, EGFR | 9 | Link | | Adenocarcinoma of lung | BRAF, EGFR, ERBB2 | 5 | Link | | SCID | JAK3, LCK | 48 | Link | n/a | Bladder cancer | EGFR, ERBB2 | 4 | Link | n/a | Immunodeficiencies | JAK3, LCK | 48 | Link | n/a | Myeloproliferative disorder | JAK2, PDGFRB | 26 | Link | n/a | Cervical cancer | EGFR, ERBB2 | 4 | Link | n/a | Pertussis | IRAK1, MAPK14 | 22 | Link | | Diabetes mellitus | INSR, PRKCD | 20 | Link | | Gastrointestinal stromal tumor | KIT, PDGFRA | 20 | Link | n/a | Medullary thyroid carcinoma | NTRK1, RET | 4 | Link | | LEOPARD syndrome | BRAF, RAF1 | 5 | Link | n/a | Alcoholism | BRAF, RAF1 | 5 | Link | | Gastric cancer | EGFR, ERBB2 | 4 | Link | | Noonan syndrome | BRAF, RAF1 | 5 | Link | n/a | Maturity onset diabetes of the young | BLK | 3 | Link | | Endometrial Cancer | ERBB2 | 1 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 2 | Link | | Osteoglophonic dysplasia | FGFR1 | 2 | Link | | Ovarian cancer | ERBB2 | 1 | Link | | Glioblastoma | ERBB2 | 1 | Link | n/a | Cholangiocarcinoma | ERBB2 | 1 | Link | | Breast cancer | ERBB2 | 1 | Link | n/a | Malignant melanoma | BRAF | 4 | Link | n/a | Noonan syndrome and related disorders | BRAF | 4 | Link | n/a | Pancreatic cancer | ERBB2 | 1 | Link | n/a | Oral cancer | EGFR | 4 | Link | n/a | Esophageal cancer | EGFR | 4 | Link | | Trigonocephaly | FGFR1 | 2 | Link | n/a | Spondylometaepiphyseal dysplasia | DDR2 | 5 | Link | n/a | Leukoencephalopathy, diffuse hereditary, with spheroids | CSF1R | 13 | Link | | Cardiofaciocutaneous syndrome | BRAF | 4 | Link | | Colorectal cancer | BRAF | 4 | Link | n/a | Laryngeal cancer | EGFR | 4 | Link | n/a | Synovial sarcoma | IGF1R | 4 | Link | | Jackson-Weiss syndrome | FGFR1 | 2 | Link | n/a | Type I diabetes mellitus | PRKCQ | 1 | Link | n/a | Renal agenesis and Renal adysplasia | RET | 3 | Link | | Hirschsprung disease | RET | 3 | Link | n/a | Pituitary tumor | PRKCA | 8 | Link | n/a | Amoebiasis | PRKCA | 8 | Link | n/a | Hypereosinophilic syndrome | PDGFRA | 16 | Link | n/a | Vibrio cholerae infection | PRKCA | 8 | Link | n/a | African trypanosomiasis | PRKCA | 8 | Link | n/a | Congenital central hypoventilation syndrome | RET | 3 | Link | | Central hypoventilation syndrome | RET | 3 | Link | n/a | Familial thoracic aortic aneurysm and dissection | TGFBR1 | 1 | Link | | Multiple self-healing squamous epithelioma | TGFBR1 | 1 | Link | n/a | Tyrosine kinase 2 deficiency | TYK2 | 1 | Link | | Loeys-Dietz syndrome | TGFBR1 | 1 | Link | | Colon cancer | SRC | 32 | Link | | Multiple endocrine neoplasia | RET | 3 | Link | | Pheochromocytoma | RET | 3 | Link | | Renal agenesis | RET | 3 | Link | n/a | Insensitivity to pain | NTRK1 | 1 | Link | | Neuroblastoma | NTRK1 | 1 | Link | n/a | Leprechaunism | INSR | 19 | Link | | Rabson-Mendenhall syndrome | INSR | 19 | Link | | Hyperinsulinemic hypoglycemia | INSR | 19 | Link | | Insulin-like growth factor I | IGF1R | 4 | Link | n/a | Malignant pleural mesothelioma | IGF1R | 4 | Link | | Kallmann syndrome | FGFR1 | 2 | Link | | Pfeiffer syndrome | FGFR1 | 2 | Link | n/a | Prion diseases | FYN | 4 | Link | | Lymphoproliferative syndrome | ITK | 1 | Link | | Polycythemia vera | JAK2 | 12 | Link | | Mastocytosis with associated hematologic disorder | KIT | 14 | Link | n/a | Amyotrophic lateral sclerosis | MAPK14 | 21 | Link | n/a | Salmonella infection | MAPK14 | 21 | Link | | Mast cell leukemia | KIT | 14 | Link | n/a | Germ cell tumors | KIT | 14 | Link | n/a | Budd-Chiari syndrome | JAK2 | 12 | Link | | Myelofibrosis | JAK2 | 12 | Link | | Thrombocythemia | JAK2 | 12 | Link | | Piebaldism | KIT | 14 | Link |
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