Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
126 |
Number of BLK related diseases |
1 |
All kinase in this family
BLK
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
| Prostate cancer | EGFR, EPHB2, ERBB2, FGFR1, FGFR2, IGF1R, INSRR, PDGFRA, PDGFRB | 73 | Link | n/a | Measles | FYN, IRAK1, IRAK4, JAK2, JAK3, PRKCQ, TYK2 | 8 | Link | n/a | Epstein-Barr virus infection | FGR, IRAK1, JAK3, LYN, MAPK14, SYK, TYK2 | 11 | Link | n/a | Tuberculosis | IRAK1, IRAK4, JAK2, MAPK14, SRC, SYK | 173 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | CSK, EGFR, LYN, MAPK14, SRC | 227 | Link | n/a | Influenza A | IRAK4, JAK2, MAPK14, PRKCA, TYK2 | 8 | Link | n/a | Toxoplasmosis | IRAK1, IRAK4, JAK2, MAPK14, TYK2 | 7 | Link | | Leukemia | ABL1, ABL2, JAK2, KIT, PDGFRB | 28 | Link | | Melanoma | EGFR, FGFR1, IGF1R, PDGFRA, PDGFRB | 73 | Link | | Neuroblastoma | ALK, NTRK1, NTRK2, NTRK3 | 16 | Link | n/a | Leishmaniasis | IRAK1, IRAK4, JAK2, MAPK14 | 7 | Link | n/a | Hepatitis C | EGFR, MAPK14, TYK2 | 70 | Link | n/a | Glioma | EGFR, PDGFRA, PDGFRB | 68 | Link | n/a | Cervical cancer | EGFR, ERBB2, FGFR3 | 68 | Link | n/a | Bladder cancer | EGFR, ERBB2, FGFR3 | 68 | Link | n/a | Immunodeficiencies | JAK3, LCK, ZAP70 | 18 | Link | | Gastric cancer | EGFR, ERBB2, FGFR2 | 68 | Link | n/a | Chagas disease | IRAK1, IRAK4, MAPK14 | 7 | Link | n/a | Choriocarcinoma | CSF1R, EGFR, ERBB2 | 68 | Link | n/a | Viral myocarditis | ABL1, ABL2, FYN | 25 | Link | n/a | Shigellosis | ABL1, MAPK14, SRC | 174 | Link | n/a | Pertussis | IRAK1, IRAK4, MAPK14 | 7 | Link | n/a | Pathogenic Escherichia coli infection | ABL1, FYN, PRKCA | 25 | Link | | LADD syndrome | FGFR2, FGFR3 | 4 | Link | | SCID | JAK3, LCK | 18 | Link | | Crouzon syndrome | FGFR2, FGFR3 | 4 | Link | | Adenocarcinoma of lung | EGFR, ERBB2 | 68 | Link | | Diabetes mellitus | INSR, PRKCD | 10 | Link | n/a | Type I diabetes mellitus | ERBB3, PRKCQ | 3 | Link | | Jackson-Weiss syndrome | FGFR1, FGFR2 | 28 | Link | | Pfeiffer syndrome | FGFR1, FGFR2 | 28 | Link | n/a | Herpes simplex infection | JAK2, TYK2 | 1 | Link | n/a | Myeloproliferative disorder | JAK2, PDGFRB | 6 | Link | n/a | Thyroid cancer | NTRK1, RET | 8 | Link | | Gastrointestinal stromal tumor | KIT, PDGFRA | 11 | Link | | Lung cancer | ALK, EGFR | 78 | Link | n/a | Medullary thyroid carcinoma | NTRK1, RET | 8 | Link | n/a | Salmonella infection | MAPK14, PKN2 | 3 | Link | | Osteoglophonic dysplasia | FGFR1 | 28 | Link | | Kallmann syndrome | FGFR1 | 28 | Link | n/a | Maturity onset diabetes of the young | BLK | 8 | Link | | Trigonocephaly | FGFR1 | 28 | Link | n/a | Chrondrodysplasia | BMPR1B | 1 | Link | | Brachydactyly | BMPR1B | 1 | Link | | Apert syndrome | FGFR2 | 4 | Link | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 4 | Link | | Hereditary hemorrhagic telangiectasia | ACVRL1 | 3 | Link | | Fibrodysplasia ossificans progressiva | ACVR1 | 3 | Link | | Craniosynostosis | FGFR2 | 4 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 4 | Link | n/a | Telangiectasia, hereditary hemorrhagic | ACVRL1 | 3 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 4 | Link | | Bent bone dysplasia syndrome | FGFR2 | 4 | Link | n/a | Lethal congenital contractural syndrome | ERBB3 | 3 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 28 | Link | | Breast cancer | ERBB2 | 9 | Link | n/a | Cholangiocarcinoma | ERBB2 | 9 | Link | | Ovarian cancer | ERBB2 | 9 | Link | | Endometrial Cancer | ERBB2 | 9 | Link | n/a | Laryngeal cancer | EGFR | 68 | Link | n/a | Saethre-Chotzen syndrome | FGFR2 | 4 | Link | n/a | Pancreatic cancer | ERBB2 | 9 | Link | n/a | Esophageal cancer | EGFR | 68 | Link | n/a | Oral cancer | EGFR | 68 | Link | n/a | Pituitary Dwarfism | BTK | 5 | Link | n/a | Agammaglobulinemias | BTK | 5 | Link | | Glioblastoma | ERBB2 | 9 | Link | | Agammaglobulinemia | BTK | 5 | Link | n/a | Spondylometaepiphyseal dysplasia | DDR2 | 4 | Link | n/a | Leukoencephalopathy, diffuse hereditary, with spheroids | CSF1R | 6 | Link | n/a | Agammaglobulinemia and isolated hormone deficiency | BTK | 5 | Link | n/a | Muenke syndrome | FGFR3 | 3 | Link | | Scaphocephaly | FGFR2 | 4 | Link | n/a | African trypanosomiasis | PRKCA | 1 | Link | n/a | Amoebiasis | PRKCA | 1 | Link | n/a | Pituitary tumor | PRKCA | 1 | Link | n/a | Renal agenesis and Renal adysplasia | RET | 7 | Link | n/a | Vibrio cholerae infection | PRKCA | 1 | Link | n/a | Hypereosinophilic syndrome | PDGFRA | 5 | Link | | Mastocytosis with associated hematologic disorder | KIT | 10 | Link | n/a | Amyotrophic lateral sclerosis | MAPK14 | 2 | Link | n/a | Insensitivity to pain | NTRK1 | 2 | Link | n/a | Obesity | NTRK2 | 2 | Link | n/a | Alcoholism | NTRK2 | 2 | Link | | Hirschsprung disease | RET | 7 | Link | n/a | Congenital central hypoventilation syndrome | RET | 7 | Link | | Colon cancer | SRC | 173 | Link | n/a | Basal cell carcinoma | STK36 | 2 | Link | n/a | Transient erythroblastopenia of childhood | TEC | 2 | Link | | Selective T-cell defect | ZAP70 | 1 | Link | n/a | Tyrosine kinase 2 deficiency | TYK2 | 1 | Link | | Mental retardation | RPS6KA3 | 1 | Link | n/a | Coffin-Lowry syndrome | RPS6KA3 | 1 | Link | | Central hypoventilation syndrome | RET | 7 | Link | | Multiple endocrine neoplasia | RET | 7 | Link | | Pheochromocytoma | RET | 7 | Link | n/a | Non-syndromic X-linked mental retardation | RPS6KA3 | 1 | Link | | Renal agenesis | RET | 7 | Link | | Mast cell leukemia | KIT | 10 | Link | n/a | Germ cell tumors | KIT | 10 | Link | n/a | Nevus | FGFR3 | 3 | Link | n/a | Spermatocytic seminoma | FGFR3 | 3 | Link | n/a | Thanatophoric dysplasia | FGFR3 | 3 | Link | n/a | Prion diseases | FYN | 7 | Link | n/a | Cancer progression/metastasis | FGFR4 | 1 | Link | n/a | Hypochondroplasia | FGFR3 | 3 | Link | | Colorectal cancer | FGFR3 | 3 | Link | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 4 | Link | n/a | Multiple myeloma | FGFR3 | 3 | Link | n/a | FGFR3-related short limb skeletal dysplasias | FGFR3 | 3 | Link | n/a | Achondroplasia | FGFR3 | 3 | Link | n/a | CATSHL syndrome | FGFR3 | 3 | Link | n/a | Malignant pleural mesothelioma | IGF1R | 3 | Link | n/a | Synovial sarcoma | IGF1R | 3 | Link | | Polycythemia vera | JAK2 | 1 | Link | n/a | Budd-Chiari syndrome | JAK2 | 1 | Link | | Myelofibrosis | JAK2 | 1 | Link | | Piebaldism | KIT | 10 | Link | | Thrombocythemia | JAK2 | 1 | Link | | Lymphoproliferative syndrome | ITK | 1 | Link | | IRAK4 deficiency | IRAK4 | 5 | Link | | Insulin-like growth factor I | IGF1R | 3 | Link | n/a | Leprechaunism | INSR | 8 | Link | | Rabson-Mendenhall syndrome | INSR | 8 | Link | n/a | Invasive pneumococcal disease | IRAK4 | 5 | Link | | Hyperinsulinemic hypoglycemia | INSR | 8 | Link |
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