Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
76 |
| Number of BTK related diseases |
4 |
All kinase in this family
BTK
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| Prostate cancer | AKT1, EGFR, ERBB2, IGF1R,
PDGFRA, PDPK1 | 19 | Link | | n/a | Measles | AKT1, JAK1, JAK2, JAK3, TYK2 | 9 | Link | | n/a | Influenza A | AKT1, JAK1, JAK2, TYK2 | 9 | Link | | Melanoma | AKT1, EGFR, IGF1R, PDGFRA | 15 | Link | | n/a | Epstein-Barr virus infection | AKT1, JAK1, JAK3, TYK2 | 9 | Link | | n/a | Hepatitis C | AKT1, EGFR, JAK1, TYK2 | 12 | Link | | n/a | Toxoplasmosis | AKT1, JAK1, JAK2, TYK2 | 9 | Link | | n/a | Tuberculosis | AKT1, JAK1, JAK2, SRC | 11 | Link | | n/a | Choriocarcinoma | CSF1R, EGFR, ERBB2 | 19 | Link | | Leukemia | AKT1, JAK2, KIT | 12 | Link | | n/a | Herpes simplex infection | JAK1, JAK2, TYK2 | 8 | Link | | Gastric cancer | EGFR, ERBB2 | 10 | Link | | n/a | Bladder cancer | EGFR, ERBB2 | 10 | Link | | n/a | Leishmaniasis | JAK1, JAK2 | 8 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | EGFR, SRC | 10 | Link | | n/a | Cervical cancer | EGFR, ERBB2 | 10 | Link | | Adenocarcinoma of lung | EGFR, ERBB2 | 10 | Link | | Colon cancer | AURKA, SRC | 23 | Link | | Hemangioma | FLT4, KDR | 11 | Link | | n/a | Glioma | EGFR, PDGFRA | 8 | Link | | n/a | Immunodeficiencies | JAK3, LCK | 18 | Link | | Ovarian cancer | AKT1, ERBB2 | 6 | Link | | Gastrointestinal stromal tumor | KIT, PDGFRA | 5 | Link | | n/a | Thyroid cancer | NTRK1, RET | 1 | Link | | Breast cancer | AKT1, ERBB2 | 6 | Link | | Lung cancer | AKT1, EGFR | 8 | Link | | SCID | JAK3, LCK | 18 | Link | | n/a | Medullary thyroid carcinoma | NTRK1, RET | 1 | Link | | Colorectal cancer | AKT1 | 1 | Link | | n/a | Laryngeal cancer | EGFR | 7 | Link | | n/a | Chagas disease | AKT1 | 1 | Link | | n/a | Esophageal cancer | EGFR | 7 | Link | | n/a | Pancreatic cancer | ERBB2 | 5 | Link | | Agammaglobulinemia | BTK | 7 | Link | | n/a | Pituitary Dwarfism | BTK | 7 | Link | | n/a | Agammaglobulinemias | BTK | 7 | Link | | n/a | Agammaglobulinemia and isolated hormone deficiency | BTK | 7 | Link | | n/a | Schizophrenia | AKT1 | 1 | Link | | n/a | Oral cancer | EGFR | 7 | Link | | n/a | Leukoencephalopathy, diffuse hereditary, with spheroids | CSF1R | 9 | Link | | n/a | Proteus syndrome | AKT1 | 1 | Link | | n/a | Lymphedemas | FLT4 | 1 | Link | | Endometrial Cancer | ERBB2 | 5 | Link | | n/a | Insensitivity to pain | NTRK1 | 1 | Link | | n/a | Hypereosinophilic syndrome | PDGFRA | 1 | Link | | Neuroblastoma | NTRK1 | 1 | Link | | Mastocytosis with associated hematologic disorder | KIT | 5 | Link | | n/a | Germ cell tumors | KIT | 5 | Link | | Mast cell leukemia | KIT | 5 | Link | | n/a | Renal agenesis and Renal adysplasia | RET | 1 | Link | | Hirschsprung disease | RET | 1 | Link | | n/a | Shigellosis | SRC | 3 | Link | | n/a | Tyrosine kinase 2 deficiency | TYK2 | 3 | Link | | Renal agenesis | RET | 1 | Link | | Pheochromocytoma | RET | 1 | Link | | n/a | Congenital central hypoventilation syndrome | RET | 1 | Link | | Central hypoventilation syndrome | RET | 1 | Link | | Multiple endocrine neoplasia | RET | 1 | Link | | Piebaldism | KIT | 5 | Link | | Thrombocythemia | JAK2 | 8 | Link | | n/a | Synovial sarcoma | IGF1R | 6 | Link | | Insulin-like growth factor I | IGF1R | 6 | Link | | n/a | Malignant pleural mesothelioma | IGF1R | 6 | Link | | n/a | Lymphedema | FLT4 | 1 | Link | | n/a | Cholangiocarcinoma | ERBB2 | 5 | Link | | Glioblastoma | ERBB2 | 5 | Link | | n/a | PTEN hamartoma tumor syndrome | AKT1 | 1 | Link | | n/a | Leprechaunism | INSR | 2 | Link | | Rabson-Mendenhall syndrome | INSR | 2 | Link | | Myelofibrosis | JAK2 | 8 | Link | | n/a | Myeloproliferative disorder | JAK2 | 8 | Link | | n/a | Budd-Chiari syndrome | JAK2 | 8 | Link | | Polycythemia vera | JAK2 | 8 | Link | | Diabetes mellitus | INSR | 2 | Link | | Hyperinsulinemic hypoglycemia | INSR | 2 | Link | | Lymphoproliferative syndrome | ITK | 11 | Link |
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