KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3EZVA_EZV (PDB code: 3EZV, chain A)
Number of involved diseases in the family	65
Number of CDK2 related diseases	5

All kinase in this family CDK2

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	AKT1, AKT2, CDC2, CDK2, CSNK2A1, GSK3B, JAK3, LYN, MAPK10, MAPK14, MAPK8	102	Link
n/a	Influenza A	AKT1, AKT2, GSK3B, IRAK4, JAK2, MAPK1, MAPK10, MAPK14, MAPK8, PRKCA, PRKCB	78	Link
n/a	Measles	AKT1, AKT2, CDK2, CDK4, CSNK2A1, FYN, GSK3B, IRAK4, JAK2, JAK3	96	Link
n/a	Tuberculosis	AKT1, AKT2, IRAK4, JAK2, MAPK1, MAPK10, MAPK14, MAPK8, SRC	91	Link
n/a	Shigellosis	ABL1, MAPK1, MAPK10, MAPK14, MAPK8, ROCK1, ROCK2, SRC	44	Link
n/a	Toxoplasmosis	AKT1, AKT2, IRAK4, JAK2, MAPK1, MAPK10, MAPK14, MAPK8	76	Link
n/a	Hepatitis C	AKT1, AKT2, GSK3B, MAPK1, MAPK10, MAPK14, MAPK8	65	Link
n/a	Chagas disease	AKT1, AKT2, IRAK4, MAPK1, MAPK10, MAPK14, MAPK8	64	Link
n/a	Salmonella infection	MAPK1, MAPK10, MAPK14, MAPK8, ROCK1, ROCK2	19	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	LYN, MAPK10, MAPK14, MAPK8, MET, SRC	28	Link
n/a	Herpes simplex infection	CDC2, CDK2, CSNK2A1, JAK2, MAPK10, MAPK8	43	Link
	Leukemia	ABL1, AKT1, AKT2, CDK4, JAK2, MAPK1	87	Link
	Melanoma	AKT1, AKT2, CDK4, FGFR1, MAPK1, MET	88	Link
	Prostate cancer	AKT1, AKT2, CDK2, FGFR1, GSK3B, MAPK1	95	Link
n/a	Leishmaniasis	IRAK4, JAK2, MAPK1, MAPK14, PRKCB	25	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA, ROCK1, ROCK2	20	Link
n/a	Pertussis	IRAK4, MAPK1, MAPK10, MAPK14, MAPK8	15	Link
	Lung cancer	AKT1, AKT2, CDK2, CDK4	78	Link
	Diabetes mellitus	AKT2, MAPK1, MAPK10, MAPK8	55	Link
	Ovarian cancer	AKT1, AKT2	49	Link
n/a	Prion diseases	FYN, MAPK1	5	Link
n/a	Amoebiasis	PRKCA, PRKCB	1	Link
	Colon cancer	AURKA, SRC	19	Link
n/a	Vibrio cholerae infection	PRKCA, PRKCB	1	Link
n/a	Viral myocarditis	ABL1, FYN	15	Link
	SCID	JAK3, LCK	27	Link
n/a	Immunodeficiencies	JAK3, LCK	27	Link
n/a	African trypanosomiasis	PRKCA, PRKCB	1	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
	Hypoinsulinemic hypoglycemia	AKT2	48	Link
n/a	Schizophrenia	AKT1	47	Link
n/a	Familial partial lipodystrophy	AKT2	48	Link
n/a	Cervical cancer	CDK4	11	Link
	Breast cancer	AKT1	47	Link
	Colorectal cancer	AKT1	47	Link
n/a	PTEN hamartoma tumor syndrome	AKT1	47	Link
n/a	Proteus syndrome	AKT1	47	Link
	Jackson-Weiss syndrome	FGFR1	24	Link
n/a	Malignant melanoma	CDK4	11	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	10	Link
n/a	Epileptic encephalopathy	MAPK10	3	Link
n/a	Early infantile epileptic encephalopathy	MAPK10	3	Link
	Thrombocythemia	JAK2	12	Link
n/a	Alcoholism	MAPK1	2	Link
	Gastric cancer	MET	2	Link
	Renal cell carcinoma	MET	2	Link
n/a	Pituitary tumor	PRKCA	1	Link
	Hepatocellular carcinoma	MET	2	Link
n/a	Autism suseptibility	MET	2	Link
n/a	Cholangiocarcinoma	MET	2	Link
n/a	Malaria	MET	2	Link
n/a	Myeloproliferative disorder	JAK2	12	Link
	Myelofibrosis	JAK2	12	Link
	Kallmann syndrome	FGFR1	24	Link
	Trigonocephaly	FGFR1	24	Link
	Osteoglophonic dysplasia	FGFR1	24	Link
n/a	Glioma	CDK4	11	Link
	Hypogonadotropic hypogonadism	FGFR1	24	Link
	Pfeiffer syndrome	FGFR1	24	Link
n/a	Basal cell carcinoma	GSK3B	2	Link
n/a	Budd-Chiari syndrome	JAK2	12	Link
	Polycythemia vera	JAK2	12	Link
	Lymphoproliferative syndrome	ITK	8	Link
n/a	Invasive pneumococcal disease	IRAK4	1	Link
	IRAK4 deficiency	IRAK4	1	Link

BioXGEM.

KIDFamMap

Allelic Variants