Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
107 |
Number of CDKL2 related diseases |
0 |
All kinase in this family
CDKL2
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
n/a | Epstein-Barr virus infection | CDC2, CDK2, CSNK2A1, CSNK2A2, GSK3B, JAK1, JAK3, MAP2K4, MAPK10, MAPK8, RIPK1 | 21 | Link | n/a | Measles | CDK2, CDK4, CSNK2A1, CSNK2A2, GSK3B, IRAK4, JAK1, JAK2, JAK3, PRKCQ | 37 | Link | n/a | Herpes simplex infection | CDC2, CDK2, CSNK2A1, CSNK2A2, JAK1, JAK2, MAPK10, MAPK8 | 15 | Link | n/a | Influenza A | GSK3B, IRAK4, JAK1, JAK2, MAP2K4, MAPK10, MAPK8, RAF1 | 9 | Link | n/a | Hepatitis C | EGFR, GSK3B, JAK1, MAPK10, MAPK8, RAF1, RIPK1 | 10 | Link | n/a | Tuberculosis | CAMK2A, IRAK4, JAK1, JAK2, MAPK10, MAPK8, RAF1 | 3 | Link | | Prostate cancer | CDK2, EGFR, FGFR1, FGFR2, GSK3B, PDPK1, RAF1 | 36 | Link | | Leukemia | ABL1, ABL2, CDK4, JAK2, RAF1, RPS6KB1 | 26 | Link | | Lung cancer | ALK, CDK2, CDK4, EGFR, PTK2 | 32 | Link | n/a | Toxoplasmosis | IRAK4, JAK1, JAK2, MAPK10, MAPK8 | 2 | Link | | Melanoma | CDK4, EGFR, FGFR1, RAF1 | 29 | Link | n/a | Alcoholism | CAMKK1, CAMKK2, NTRK2, RAF1 | 2 | Link | | Diabetes mellitus | MAPK10, MAPK8, PRKCD, PRKCZ | 6 | Link | n/a | Chagas disease | IRAK4, MAP2K4, MAPK10, MAPK8 | 1 | Link | | Neuroblastoma | ALK, NTRK1, NTRK2, NTRK3 | 3 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | EGFR, MAP2K4, MAPK10, MAPK8 | 3 | Link | n/a | Pertussis | IRAK4, MAPK10, MAPK8 | 1 | Link | n/a | Salmonella infection | MAPK10, MAPK8, PKN2 | 1 | Link | n/a | Cardiomyopathy | MYLK2, PRKAA1, PRKAA2 | 1 | Link | n/a | Leishmaniasis | IRAK4, JAK1, JAK2 | 2 | Link | n/a | Immunodeficiencies | JAK3, LCK, ZAP70 | 11 | Link | n/a | Cervical cancer | CDK4, EGFR, FGFR3 | 23 | Link | n/a | Shigellosis | ABL1, MAPK10, MAPK8 | 4 | Link | | Gastric cancer | EGFR, FGFR2 | 3 | Link | | Pfeiffer syndrome | FGFR1, FGFR2 | 6 | Link | | Jackson-Weiss syndrome | FGFR1, FGFR2 | 6 | Link | n/a | Viral myocarditis | ABL1, ABL2 | 4 | Link | n/a | Thyroid cancer | NTRK1, RET | 3 | Link | n/a | Bladder cancer | EGFR, FGFR3 | 3 | Link | | SCID | JAK3, LCK | 11 | Link | n/a | Medullary thyroid carcinoma | NTRK1, RET | 3 | Link | n/a | Glioma | CDK4, EGFR | 23 | Link | | LADD syndrome | FGFR2, FGFR3 | 2 | Link | | Crouzon syndrome | FGFR2, FGFR3 | 2 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 1 | Link | | Trigonocephaly | FGFR1 | 6 | Link | | Bent bone dysplasia syndrome | FGFR2 | 1 | Link | n/a | Pathogenic Escherichia coli infection | ABL1 | 4 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 1 | Link | | Kallmann syndrome | FGFR1 | 6 | Link | | Apert syndrome | FGFR2 | 1 | Link | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 1 | Link | | Craniosynostosis | FGFR2 | 1 | Link | | Colon cancer | AURKA | 37 | Link | | Osteoglophonic dysplasia | FGFR1 | 6 | Link | n/a | Saethre-Chotzen syndrome | FGFR2 | 1 | Link | n/a | Esophageal cancer | EGFR | 2 | Link | n/a | Oral cancer | EGFR | 2 | Link | n/a | Agammaglobulinemia and isolated hormone deficiency | BTK | 1 | Link | n/a | Malignant melanoma | CDK4 | 21 | Link | n/a | Cocaine addiction | CDK5 | 2 | Link | n/a | Choriocarcinoma | EGFR | 2 | Link | n/a | Laryngeal cancer | EGFR | 2 | Link | n/a | Maturity onset diabetes of the young | BLK | 1 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 6 | Link | n/a | Agammaglobulinemias | BTK | 1 | Link | | Adenocarcinoma of lung | EGFR | 2 | Link | | Agammaglobulinemia | BTK | 1 | Link | n/a | Pituitary Dwarfism | BTK | 1 | Link | | Colorectal cancer | FGFR3 | 2 | Link | | Scaphocephaly | FGFR2 | 1 | Link | n/a | Cirrhosis due to liver phosphorylase kinase deficiency | PHKG2 | 1 | Link | | Glycogen storage disease | PHKG2 | 1 | Link | n/a | Type I diabetes mellitus | PRKCQ | 2 | Link | n/a | Amoebiasis | PTK2 | 1 | Link | n/a | Glycogen storage diseases | PHKG2 | 1 | Link | n/a | Obesity | NTRK2 | 1 | Link | n/a | Epileptic encephalopathy | MAPK10 | 1 | Link | n/a | Familial thoracic aortic aneurysm and dissection | MYLK | 1 | Link | n/a | Aortic aneurysm | MYLK | 1 | Link | n/a | Insensitivity to pain | NTRK1 | 2 | Link | | LEOPARD syndrome | RAF1 | 1 | Link | | Noonan syndrome | RAF1 | 1 | Link | | Renal agenesis | RET | 2 | Link | | Venous malformations | TEK | 2 | Link | n/a | Rheumatoid arthritis | TEK | 2 | Link | | Selective T-cell defect | ZAP70 | 1 | Link | | Pheochromocytoma | RET | 2 | Link | | Multiple endocrine neoplasia | RET | 2 | Link | n/a | Renal agenesis and Renal adysplasia | RET | 2 | Link | | Hirschsprung disease | RET | 2 | Link | n/a | Congenital central hypoventilation syndrome | RET | 2 | Link | | Central hypoventilation syndrome | RET | 2 | Link | n/a | Early infantile epileptic encephalopathy | MAPK10 | 1 | Link | | Thrombocythemia | JAK2 | 2 | Link | n/a | Muenke syndrome | FGFR3 | 2 | Link | n/a | Nevus | FGFR3 | 2 | Link | n/a | Spermatocytic seminoma | FGFR3 | 2 | Link | n/a | Thanatophoric dysplasia | FGFR3 | 2 | Link | n/a | Hypochondroplasia | FGFR3 | 2 | Link | n/a | Achondroplasia | FGFR3 | 2 | Link | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 1 | Link | n/a | Multiple myeloma | FGFR3 | 2 | Link | n/a | FGFR3-related short limb skeletal dysplasias | FGFR3 | 2 | Link | n/a | CATSHL syndrome | FGFR3 | 2 | Link | n/a | Cancer progression/metastasis | FGFR4 | 1 | Link | n/a | Congenital stationary night blindness | GRK1 | 1 | Link | | Polycythemia vera | JAK2 | 2 | Link | n/a | Budd-Chiari syndrome | JAK2 | 2 | Link | | Myelofibrosis | JAK2 | 2 | Link | n/a | Myeloproliferative disorder | JAK2 | 2 | Link | | Lymphoproliferative syndrome | ITK | 5 | Link | | IRAK4 deficiency | IRAK4 | 1 | Link | n/a | Oguchi disease | GRK1 | 1 | Link | n/a | Basal cell carcinoma | GSK3B | 7 | Link | n/a | Endocrine-cerebroosteodysplasia | ICK | 1 | Link | n/a | Invasive pneumococcal disease | IRAK4 | 1 | Link |
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