KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3F5PA_741 (PDB code: 3F5P, chain A)
Number of involved diseases in the family	81
Number of DDR1 related diseases	0

All kinase in this family DDR1

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	EGFR, EPHB2, FGFR1, IGF1R, INSRR	79	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	4	Link
	Lung cancer	ALK, EGFR, PTK2	40	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, SRC	76	Link
	Melanoma	EGFR, FGFR1, IGF1R	79	Link
n/a	Immunodeficiencies	LCK, ZAP70	3	Link
n/a	Hepatitis C	EGFR, TYK2	39	Link
n/a	Herpes simplex infection	JAK2, TYK2	1	Link
n/a	Influenza A	JAK2, TYK2	1	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	3	Link
	Hemangioma	FLT4, KDR	22	Link
	Leukemia	ABL1, JAK2	6	Link
n/a	Toxoplasmosis	JAK2, TYK2	1	Link
n/a	Measles	JAK2, TYK2	1	Link
n/a	Tuberculosis	JAK2, SRC	41	Link
n/a	Thyroid cancer	NTRK1, RET	3	Link
n/a	Shigellosis	ABL1, SRC	41	Link
	Osteoglophonic dysplasia	FGFR1	1	Link
n/a	Viral myocarditis	ABL1	6	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
n/a	Agammaglobulinemias	BTK	3	Link
n/a	Pituitary Dwarfism	BTK	3	Link
	Trigonocephaly	FGFR1	1	Link
n/a	Bladder cancer	EGFR	39	Link
n/a	Pathogenic Escherichia coli infection	ABL1	6	Link
n/a	Lymphedemas	FLT4	16	Link
	Pfeiffer syndrome	FGFR1	1	Link
	Jackson-Weiss syndrome	FGFR1	1	Link
	Kallmann syndrome	FGFR1	1	Link
	Agammaglobulinemia	BTK	3	Link
	Hypogonadotropic hypogonadism	FGFR1	1	Link
	Gastric cancer	EGFR	39	Link
n/a	Laryngeal cancer	EGFR	39	Link
n/a	Glioma	EGFR	39	Link
n/a	Choriocarcinoma	EGFR	39	Link
n/a	Cervical cancer	EGFR	39	Link
n/a	Esophageal cancer	EGFR	39	Link
n/a	Lymphedema	FLT4	16	Link
n/a	Type I diabetes mellitus	ERBB3	1	Link
n/a	Lethal congenital contractural syndrome	ERBB3	1	Link
	Adenocarcinoma of lung	EGFR	39	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	3	Link
n/a	Oral cancer	EGFR	39	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	1	Link
	Rabson-Mendenhall syndrome	INSR	1	Link
n/a	Malignant pleural mesothelioma	IGF1R	40	Link
	Renal agenesis	RET	2	Link
n/a	Non-syndromic X-linked mental retardation	RPS6KA3	1	Link
	Pheochromocytoma	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
n/a	Coffin-Lowry syndrome	RPS6KA3	1	Link
	Mental retardation	RPS6KA3	1	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	1	Link
	Selective T-cell defect	ZAP70	1	Link
n/a	Epstein-Barr virus infection	TYK2	1	Link
n/a	Rheumatoid arthritis	TEK	29	Link
	Colon cancer	SRC	41	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Venous malformations	TEK	29	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
n/a	Amoebiasis	PTK2	2	Link
	Lymphoproliferative syndrome	ITK	1	Link
	Polycythemia vera	JAK2	1	Link
	Hyperinsulinemic hypoglycemia	INSR	1	Link
	Diabetes mellitus	INSR	1	Link
n/a	Synovial sarcoma	IGF1R	40	Link
	Insulin-like growth factor I	IGF1R	40	Link
n/a	Leprechaunism	INSR	1	Link
n/a	Leishmaniasis	JAK2	1	Link
n/a	Budd-Chiari syndrome	JAK2	1	Link
n/a	Insensitivity to pain	NTRK1	2	Link
n/a	Alcoholism	NTRK2	2	Link
n/a	Obesity	NTRK2	2	Link
	Retinitis pigmentosa	MERTK	2	Link
	SCID	LCK	3	Link
	Myelofibrosis	JAK2	1	Link
n/a	Myeloproliferative disorder	JAK2	1	Link
	Thrombocythemia	JAK2	1	Link

BioXGEM.

KIDFamMap

Allelic Variants