Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
75 |
Number of FRK related diseases |
0 |
All kinase in this family
FRK
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
| Leukemia | ABL1, ABL2, BRAF, JAK2, KIT, PDGFRB | 86 | Link | n/a | Epstein-Barr virus infection | FGR, JAK3, LYN, SYK, TYK2 | 47 | Link | | Melanoma | BRAF, EGFR, FGFR1, PDGFRA, PDGFRB | 29 | Link | | Prostate cancer | BRAF, EGFR, FGFR1, PDGFRA, PDGFRB | 29 | Link | n/a | Measles | FYN, JAK2, JAK3, TYK2 | 22 | Link | n/a | Tuberculosis | JAK2, SRC, SYK | 65 | Link | n/a | Hepatitis C | BRAF, EGFR, TYK2 | 7 | Link | n/a | Influenza A | JAK2, PRKCA, TYK2 | 24 | Link | n/a | Glioma | EGFR, PDGFRA, PDGFRB | 27 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | EGFR, LYN, SRC | 57 | Link | | Lung cancer | ALK, BRAF, EGFR | 8 | Link | n/a | Pathogenic Escherichia coli infection | ABL1, FYN, PRKCA | 59 | Link | n/a | Viral myocarditis | ABL1, ABL2, FYN | 56 | Link | n/a | Immunodeficiencies | JAK3, LCK | 68 | Link | | SCID | JAK3, LCK | 68 | Link | n/a | Herpes simplex infection | JAK2, TYK2 | 18 | Link | n/a | Myeloproliferative disorder | JAK2, PDGFRB | 31 | Link | n/a | Toxoplasmosis | JAK2, TYK2 | 18 | Link | | Adenocarcinoma of lung | BRAF, EGFR | 7 | Link | | Gastrointestinal stromal tumor | KIT, PDGFRA | 20 | Link | n/a | Choriocarcinoma | CSF1R, EGFR | 15 | Link | n/a | Thyroid cancer | BRAF, RET | 7 | Link | n/a | Shigellosis | ABL1, SRC | 99 | Link | n/a | Laryngeal cancer | EGFR | 5 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 2 | Link | n/a | Leukoencephalopathy, diffuse hereditary, with spheroids | CSF1R | 14 | Link | n/a | Oral cancer | EGFR | 5 | Link | | Gastric cancer | EGFR | 5 | Link | n/a | Bladder cancer | EGFR | 5 | Link | n/a | Esophageal cancer | EGFR | 5 | Link | n/a | Cervical cancer | EGFR | 5 | Link | | Colorectal cancer | BRAF | 5 | Link | | Noonan syndrome | BRAF | 5 | Link | n/a | Noonan syndrome and related disorders | BRAF | 5 | Link | n/a | Malignant melanoma | BRAF | 5 | Link | n/a | Maturity onset diabetes of the young | BLK | 3 | Link | | Neuroblastoma | ALK | 1 | Link | n/a | Alcoholism | BRAF | 5 | Link | n/a | Tyrosine kinase 2 deficiency | TYK2 | 1 | Link | | LEOPARD syndrome | BRAF | 5 | Link | | Osteoglophonic dysplasia | FGFR1 | 2 | Link | | Cardiofaciocutaneous syndrome | BRAF | 5 | Link | | Colon cancer | SRC | 46 | Link | | Pfeiffer syndrome | FGFR1 | 2 | Link | | Trigonocephaly | FGFR1 | 2 | Link | n/a | Hypereosinophilic syndrome | PDGFRA | 16 | Link | n/a | Vibrio cholerae infection | PRKCA | 6 | Link | | Mastocytosis with associated hematologic disorder | KIT | 14 | Link | | Mast cell leukemia | KIT | 14 | Link | | Piebaldism | KIT | 14 | Link | n/a | Germ cell tumors | KIT | 14 | Link | n/a | African trypanosomiasis | PRKCA | 6 | Link | n/a | Amoebiasis | PRKCA | 6 | Link | | Central hypoventilation syndrome | RET | 2 | Link | n/a | Medullary thyroid carcinoma | RET | 2 | Link | n/a | Congenital central hypoventilation syndrome | RET | 2 | Link | | Hirschsprung disease | RET | 2 | Link | n/a | Pituitary tumor | PRKCA | 6 | Link | n/a | Renal agenesis and Renal adysplasia | RET | 2 | Link | | Thrombocythemia | JAK2 | 17 | Link | | Myelofibrosis | JAK2 | 17 | Link | n/a | Prion diseases | FYN | 4 | Link | | Pheochromocytoma | RET | 2 | Link | | Renal agenesis | RET | 2 | Link | | Multiple endocrine neoplasia | RET | 2 | Link | | Jackson-Weiss syndrome | FGFR1 | 2 | Link | | Kallmann syndrome | FGFR1 | 2 | Link | n/a | Leprechaunism | INSR | 29 | Link | | Rabson-Mendenhall syndrome | INSR | 29 | Link | n/a | Leishmaniasis | JAK2 | 17 | Link | n/a | Budd-Chiari syndrome | JAK2 | 17 | Link | | Polycythemia vera | JAK2 | 17 | Link | | Lymphoproliferative syndrome | ITK | 3 | Link | | Diabetes mellitus | INSR | 29 | Link | | Hyperinsulinemic hypoglycemia | INSR | 29 | Link |
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