Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
69 |
| Number of LCK related diseases |
2 |
All kinase in this family
LCK
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| Leukemia | ABL1, ABL2, BRAF, KIT,
PDGFRB | 88 | Link | | Melanoma | BRAF, FGFR1, MET, PDGFRA,
PDGFRB | 10 | Link | | Prostate cancer | BRAF, FGFR1, PDGFRA, PDGFRB | 9 | Link | | n/a | Shigellosis | ABL1, MAPK14, SRC | 135 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | MAPK14, MET, SRC | 69 | Link | | n/a | Hepatitis C | BRAF, MAPK14, RIPK1 | 51 | Link | | n/a | Tuberculosis | MAPK14, SRC | 68 | Link | | Neuroblastoma | NTRK2, NTRK3 | 2 | Link | | n/a | Viral myocarditis | ABL1, ABL2 | 74 | Link | | n/a | Epstein-Barr virus infection | MAPK14, RIPK1 | 47 | Link | | n/a | Glioma | PDGFRA, PDGFRB | 4 | Link | | Gastrointestinal stromal tumor | KIT, PDGFRA | 13 | Link | | n/a | Rheumatoid arthritis | FLT1, TEK | 37 | Link | | Hemangioma | FLT4, KDR | 55 | Link | | Colon cancer | AURKA, SRC | 31 | Link | | n/a | Alcoholism | BRAF, NTRK2 | 7 | Link | | n/a | Leukoencephalopathy, diffuse hereditary, with spheroids | CSF1R | 7 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 4 | Link | | n/a | Choriocarcinoma | CSF1R | 7 | Link | | Jackson-Weiss syndrome | FGFR1 | 4 | Link | | Osteoglophonic dysplasia | FGFR1 | 4 | Link | | Pfeiffer syndrome | FGFR1 | 4 | Link | | Kallmann syndrome | FGFR1 | 4 | Link | | n/a | Agammaglobulinemia and isolated hormone deficiency | BTK | 2 | Link | | Trigonocephaly | FGFR1 | 4 | Link | | Lung cancer | BRAF | 7 | Link | | Agammaglobulinemia | BTK | 2 | Link | | n/a | Noonan syndrome and related disorders | BRAF | 7 | Link | | n/a | Malignant melanoma | BRAF | 7 | Link | | n/a | Thyroid cancer | BRAF | 7 | Link | | n/a | Pathogenic Escherichia coli infection | ABL1 | 74 | Link | | Adenocarcinoma of lung | BRAF | 7 | Link | | Cardiofaciocutaneous syndrome | BRAF | 7 | Link | | n/a | Pituitary Dwarfism | BTK | 2 | Link | | n/a | Agammaglobulinemias | BTK | 2 | Link | | Noonan syndrome | BRAF | 7 | Link | | Colorectal cancer | BRAF | 7 | Link | | LEOPARD syndrome | BRAF | 7 | Link | | n/a | Leprechaunism | INSR | 16 | Link | | n/a | Lymphedemas | FLT4 | 3 | Link | | n/a | Malaria | MET | 3 | Link | | n/a | Cholangiocarcinoma | MET | 3 | Link | | Renal cell carcinoma | MET | 3 | Link | | n/a | Influenza A | MAPK14 | 47 | Link | | Gastric cancer | MET | 3 | Link | | n/a | Autism suseptibility | MET | 3 | Link | | Hepatocellular carcinoma | MET | 3 | Link | | n/a | Myeloproliferative disorder | PDGFRB | 4 | Link | | Venous malformations | TEK | 37 | Link | | n/a | Hypereosinophilic syndrome | PDGFRA | 3 | Link | | n/a | Obesity | NTRK2 | 2 | Link | | n/a | Congenital myasthenic syndrome | MUSK | 2 | Link | | n/a | Myasthenic syndrome | MUSK | 2 | Link | | n/a | Toxoplasmosis | MAPK14 | 47 | Link | | n/a | Chagas disease | MAPK14 | 47 | Link | | Piebaldism | KIT | 12 | Link | | n/a | Germ cell tumors | KIT | 12 | Link | | Hyperinsulinemic hypoglycemia | INSR | 16 | Link | | Diabetes mellitus | INSR | 16 | Link | | n/a | Lymphedema | FLT4 | 3 | Link | | Rabson-Mendenhall syndrome | INSR | 16 | Link | | Mast cell leukemia | KIT | 12 | Link | | Mastocytosis with associated hematologic disorder | KIT | 12 | Link | | n/a | Pertussis | MAPK14 | 47 | Link | | n/a | Leishmaniasis | MAPK14 | 47 | Link | | n/a | Salmonella infection | MAPK14 | 47 | Link | | n/a | Amyotrophic lateral sclerosis | MAPK14 | 47 | Link | | n/a | Immunodeficiencies | LCK | 85 | Link | | SCID | LCK | 85 | Link |
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