Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
65 |
Number of MELK related diseases |
0 |
All kinase in this family
MELK
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
| Leukemia | ABL1, ABL2, CDK4, CDK6, JAK2, PIM1, RAF1, RPS6KB1, RPS6KB2 | 9 | Link | n/a | Tuberculosis | CAMK2A, CAMK2G, JAK1, JAK2, MAPK10, MAPK8, MAPK9, RAF1, SYK | 4 | Link | n/a | Epstein-Barr virus infection | CDC2, CDK2, GSK3B, JAK1, JAK3, MAPK10, MAPK8, MAPK9, SYK | 24 | Link | n/a | Herpes simplex infection | CDC2, CDK2, JAK1, JAK2, MAPK10, MAPK8, MAPK9 | 18 | Link | n/a | Influenza A | GSK3B, JAK1, JAK2, MAPK10, MAPK8, MAPK9, RAF1 | 10 | Link | n/a | Measles | CDK2, CDK4, CDK6, GSK3B, JAK1, JAK2, JAK3 | 26 | Link | n/a | Hepatitis C | GSK3B, JAK1, MAPK10, MAPK8, MAPK9, RAF1 | 10 | Link | | Prostate cancer | CDK2, CHEK2, GSK3B, PDPK1, RAF1 | 20 | Link | n/a | Toxoplasmosis | JAK1, JAK2, MAPK10, MAPK8, MAPK9 | 3 | Link | n/a | Alcoholism | CAMKK1, CAMKK2, NTRK2, RAF1 | 2 | Link | | Diabetes mellitus | MAPK10, MAPK8, MAPK9, PRKCD | 3 | Link | | Lung cancer | ALK, CDK2, CDK4, CDK6 | 17 | Link | | Neuroblastoma | ALK, NTRK1, NTRK2, NTRK3 | 1 | Link | n/a | Shigellosis | ABL1, MAPK10, MAPK8, MAPK9 | 2 | Link | n/a | Pertussis | MAPK10, MAPK8, MAPK9 | 1 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | MAPK10, MAPK8, MAPK9 | 1 | Link | n/a | Salmonella infection | MAPK10, MAPK8, MAPK9 | 1 | Link | | Melanoma | CDK4, CDK6, RAF1 | 9 | Link | n/a | Chagas disease | MAPK10, MAPK8, MAPK9 | 1 | Link | n/a | Medullary thyroid carcinoma | NTRK1, RET | 1 | Link | n/a | Thyroid cancer | NTRK1, RET | 1 | Link | n/a | Leishmaniasis | JAK1, JAK2 | 2 | Link | n/a | Viral myocarditis | ABL1, ABL2 | 2 | Link | | Breast cancer | CHEK2 | 1 | Link | | Osteosarcoma | CHEK2 | 1 | Link | n/a | Cocaine addiction | CDK5 | 4 | Link | | Li-Fraumeni syndrome | CHEK2 | 1 | Link | n/a | Cervical cancer | CDK4 | 8 | Link | n/a | Glioma | CDK4 | 8 | Link | n/a | Agammaglobulinemias | BTK | 1 | Link | | Colon cancer | AURKA | 9 | Link | n/a | Pathogenic Escherichia coli infection | ABL1 | 1 | Link | n/a | Pituitary Dwarfism | BTK | 1 | Link | | Agammaglobulinemia | BTK | 1 | Link | n/a | Malignant melanoma | CDK4 | 8 | Link | n/a | Basal cell carcinoma | GSK3B | 7 | Link | n/a | Agammaglobulinemia and isolated hormone deficiency | BTK | 1 | Link | n/a | Budd-Chiari syndrome | JAK2 | 1 | Link | | Lymphoproliferative syndrome | ITK | 6 | Link | | Hirschsprung disease | RET | 1 | Link | n/a | Renal agenesis and Renal adysplasia | RET | 1 | Link | | Noonan syndrome | RAF1 | 1 | Link | | Glycogen storage disease | PHKG2 | 1 | Link | | LEOPARD syndrome | RAF1 | 1 | Link | n/a | Congenital central hypoventilation syndrome | RET | 1 | Link | | Central hypoventilation syndrome | RET | 1 | Link | n/a | Rheumatoid arthritis | TEK | 27 | Link | | Venous malformations | TEK | 27 | Link | | Renal agenesis | RET | 1 | Link | | Multiple endocrine neoplasia | RET | 1 | Link | | Pheochromocytoma | RET | 1 | Link | n/a | Cirrhosis due to liver phosphorylase kinase deficiency | PHKG2 | 1 | Link | n/a | Glycogen storage diseases | PHKG2 | 1 | Link | n/a | Immunodeficiencies | JAK3 | 6 | Link | | Thrombocythemia | JAK2 | 1 | Link | n/a | Myeloproliferative disorder | JAK2 | 1 | Link | | Polycythemia vera | JAK2 | 1 | Link | | Myelofibrosis | JAK2 | 1 | Link | | SCID | JAK3 | 6 | Link | n/a | Early infantile epileptic encephalopathy | MAPK10 | 1 | Link | n/a | Obesity | NTRK2 | 1 | Link | n/a | Insensitivity to pain | NTRK1 | 1 | Link | n/a | Aortic aneurysm | MYLK | 5 | Link | n/a | Epileptic encephalopathy | MAPK10 | 1 | Link | n/a | Familial thoracic aortic aneurysm and dissection | MYLK | 5 | Link |
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