Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
99 |
Number of NEK1 related diseases |
1 |
All kinase in this family
NEK1
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
| Prostate cancer | EGFR, EPHB2, FGFR2, IGF1R, INSRR, PDPK1 | 42 | Link | n/a | Amoebiasis | PRKACA, PRKACG, PRKCA, PRKX, PTK2 | 59 | Link | n/a | Epstein-Barr virus infection | LYN, PRKACA, PRKACG, PRKX, SYK | 11 | Link | | Leukemia | ABL1, ABL2, JAK2, TGFBR1 | 12 | Link | n/a | Vibrio cholerae infection | PRKACA, PRKACG, PRKCA, PRKX | 58 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | CSK, EGFR, LYN, SRC | 41 | Link | | Neuroblastoma | ALK, NTRK1, NTRK2, NTRK3 | 16 | Link | n/a | Tuberculosis | IRAK4, JAK2, SRC, SYK | 21 | Link | | Lung cancer | ALK, EGFR, PTK2, ROS1 | 40 | Link | n/a | Cardiomyopathy | PRKACA, PRKACG, PRKX | 8 | Link | n/a | Influenza A | IRAK4, JAK2, PRKCA | 60 | Link | n/a | Prion diseases | PRKACA, PRKACG, PRKX | 8 | Link | n/a | Cocaine addiction | PRKACA, PRKACG, PRKX | 8 | Link | n/a | Bladder cancer | EGFR, FGFR3 | 38 | Link | | Gastric cancer | EGFR, FGFR2 | 39 | Link | n/a | Leishmaniasis | IRAK4, JAK2 | 11 | Link | n/a | Chagas disease | IRAK4, TGFBR1 | 4 | Link | n/a | Toxoplasmosis | IRAK4, JAK2 | 11 | Link | n/a | Cervical cancer | EGFR, FGFR3 | 38 | Link | n/a | Measles | IRAK4, JAK2 | 11 | Link | | Melanoma | EGFR, IGF1R | 38 | Link | | Diabetes mellitus | INSR, PRKCE | 12 | Link | | Crouzon syndrome | FGFR2, FGFR3 | 8 | Link | n/a | Alcoholism | NTRK2, PRKACA | 10 | Link | | Colon cancer | AURKA, SRC | 19 | Link | | LADD syndrome | FGFR2, FGFR3 | 8 | Link | n/a | Viral myocarditis | ABL1, ABL2 | 9 | Link | n/a | Shigellosis | ABL1, SRC | 20 | Link | n/a | Pathogenic Escherichia coli infection | ABL1, PRKCA | 59 | Link | | Scaphocephaly | FGFR2 | 8 | Link | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 8 | Link | n/a | Saethre-Chotzen syndrome | FGFR2 | 8 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 8 | Link | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 8 | Link | | Craniosynostosis | FGFR2 | 8 | Link | | Jackson-Weiss syndrome | FGFR2 | 8 | Link | | Bent bone dysplasia syndrome | FGFR2 | 8 | Link | | Pfeiffer syndrome | FGFR2 | 8 | Link | | Apert syndrome | FGFR2 | 8 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 8 | Link | n/a | Glioma | EGFR | 38 | Link | | Adenocarcinoma of lung | EGFR | 38 | Link | n/a | Pituitary Dwarfism | BTK | 5 | Link | | Agammaglobulinemia | BTK | 5 | Link | n/a | Agammaglobulinemias | BTK | 5 | Link | n/a | Maturity onset diabetes of the young | BLK | 8 | Link | | Fibrodysplasia ossificans progressiva | ACVR1 | 3 | Link | n/a | Pancreatic cancer | ACVR1B | 2 | Link | n/a | Agammaglobulinemia and isolated hormone deficiency | BTK | 5 | Link | n/a | Spondylometaepiphyseal dysplasia | DDR2 | 3 | Link | n/a | Laryngeal cancer | EGFR | 38 | Link | n/a | Hepatitis C | EGFR | 38 | Link | n/a | Multiple myeloma | FGFR3 | 7 | Link | n/a | Choriocarcinoma | EGFR | 38 | Link | n/a | Oral cancer | EGFR | 38 | Link | n/a | Esophageal cancer | EGFR | 38 | Link | n/a | Spermatocytic seminoma | FGFR3 | 7 | Link | n/a | FGFR3-related short limb skeletal dysplasias | FGFR3 | 7 | Link | n/a | Short rib-polydactyly syndorme | NEK1 | 3 | Link | n/a | Nephronophthisis-medullary cystic kidney disease | NEK8 | 1 | Link | n/a | Nephronophthisis | NEK8 | 1 | Link | n/a | Myasthenic syndrome | MUSK | 5 | Link | n/a | Congenital myasthenic syndrome | MUSK | 5 | Link | n/a | Myeloproliferative disorder | JAK2 | 10 | Link | | Thrombocythemia | JAK2 | 10 | Link | n/a | Amyotrophic lateral sclerosis | MAP3K5 | 6 | Link | n/a | Thyroid cancer | NTRK1 | 15 | Link | n/a | Insensitivity to pain | NTRK1 | 15 | Link | | Loeys-Dietz syndrome | TGFBR1 | 2 | Link | n/a | Familial thoracic aortic aneurysm and dissection | TGFBR1 | 2 | Link | | Multiple self-healing squamous epithelioma | TGFBR1 | 2 | Link | n/a | Transient erythroblastopenia of childhood | TEC | 2 | Link | n/a | Pituitary tumor | PRKCA | 55 | Link | n/a | Medullary thyroid carcinoma | NTRK1 | 15 | Link | n/a | Obesity | NTRK2 | 9 | Link | n/a | Salmonella infection | PKN1 | 11 | Link | n/a | African trypanosomiasis | PRKCA | 55 | Link | | Myelofibrosis | JAK2 | 10 | Link | n/a | Budd-Chiari syndrome | JAK2 | 10 | Link | n/a | Thanatophoric dysplasia | FGFR3 | 7 | Link | n/a | Cancer progression/metastasis | FGFR4 | 3 | Link | n/a | Malignant pleural mesothelioma | IGF1R | 5 | Link | n/a | Nevus | FGFR3 | 7 | Link | n/a | Muenke syndrome | FGFR3 | 7 | Link | n/a | CATSHL syndrome | FGFR3 | 7 | Link | n/a | Achondroplasia | FGFR3 | 7 | Link | | Colorectal cancer | FGFR3 | 7 | Link | n/a | Hypochondroplasia | FGFR3 | 7 | Link | n/a | Synovial sarcoma | IGF1R | 5 | Link | | Insulin-like growth factor I | IGF1R | 5 | Link | | Lymphoproliferative syndrome | ITK | 6 | Link | | Polycythemia vera | JAK2 | 10 | Link | n/a | Herpes simplex infection | JAK2 | 10 | Link | | IRAK4 deficiency | IRAK4 | 4 | Link | n/a | Invasive pneumococcal disease | IRAK4 | 4 | Link | n/a | Leprechaunism | INSR | 5 | Link | | Rabson-Mendenhall syndrome | INSR | 5 | Link | | Hyperinsulinemic hypoglycemia | INSR | 5 | Link | n/a | Pertussis | IRAK4 | 4 | Link |
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