KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2C6EA_HPM (PDB code: 2C6E, chain A)
Number of involved diseases in the family	90
Number of PLK3 related diseases	1

All kinase in this family PLK3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	CDK2, CHEK2, EGFR, FGFR1, FGFR2, RAF1	56	Link
n/a	Tuberculosis	JAK2, MAPK8, MAPK9, PLK3, RAF1	11	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, MAPK8, MAPK9	49	Link
	Leukemia	ABL1, JAK2, RAF1, RPS6KB1	9	Link
n/a	Influenza A	JAK2, MAPK8, MAPK9, RAF1	9	Link
n/a	Hepatitis C	EGFR, MAPK8, MAPK9, RAF1	50	Link
	Lung cancer	ALK, CDK2, EGFR, PTK2	53	Link
n/a	Measles	CDK2, JAK2, JAK3, PRKCQ	15	Link
n/a	Epstein-Barr virus infection	CDK2, JAK3, MAPK8, MAPK9	8	Link
n/a	Herpes simplex infection	CDK2, JAK2, MAPK8, MAPK9	8	Link
n/a	Toxoplasmosis	JAK2, MAPK8, MAPK9	7	Link
	Diabetes mellitus	MAPK8, MAPK9, PRKCD	11	Link
	Melanoma	EGFR, FGFR1, RAF1	48	Link
n/a	Shigellosis	ABL1, MAPK8, MAPK9	6	Link
n/a	Immunodeficiencies	JAK3, LCK	54	Link
	Pfeiffer syndrome	FGFR1, FGFR2	5	Link
	Crouzon syndrome	FGFR2, FGFR3	5	Link
	Gastric cancer	EGFR, FGFR2	49	Link
n/a	Bladder cancer	EGFR, FGFR3	45	Link
n/a	Cervical cancer	EGFR, FGFR3	45	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	5	Link
	LADD syndrome	FGFR2, FGFR3	5	Link
n/a	Chagas disease	MAPK8, MAPK9	3	Link
n/a	Pertussis	MAPK8, MAPK9	3	Link
	SCID	JAK3, LCK	54	Link
n/a	Salmonella infection	MAPK8, MAPK9	3	Link
n/a	Medullary thyroid carcinoma	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
n/a	Esophageal cancer	EGFR	45	Link
	Osteosarcoma	CHEK2	4	Link
n/a	Oral cancer	EGFR	45	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Choriocarcinoma	EGFR	45	Link
	Adenocarcinoma of lung	EGFR	45	Link
	Hypogonadotropic hypogonadism	FGFR1	1	Link
n/a	Thyroid cancer	RET	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
	Breast cancer	CHEK2	4	Link
n/a	Glioma	EGFR	45	Link
n/a	Laryngeal cancer	EGFR	45	Link
	Multiple endocrine neoplasia	RET	2	Link
	Li-Fraumeni syndrome	CHEK2	4	Link
	Neuroblastoma	ALK	4	Link
	Colon cancer	AURKA	102	Link
	Venous malformations	TEK	25	Link
n/a	Viral myocarditis	ABL1	3	Link
n/a	Pathogenic Escherichia coli infection	ABL1	3	Link
n/a	Rheumatoid arthritis	TEK	25	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
n/a	Agammaglobulinemias	BTK	4	Link
	Renal agenesis	RET	2	Link
	Pheochromocytoma	RET	2	Link
n/a	Basal cell carcinoma	STK36	2	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	4	Link
n/a	Pituitary Dwarfism	BTK	4	Link
	Agammaglobulinemia	BTK	4	Link
	Trigonocephaly	FGFR1	1	Link
	Osteoglophonic dysplasia	FGFR1	1	Link
n/a	Nevus	FGFR3	1	Link
n/a	Spermatocytic seminoma	FGFR3	1	Link
n/a	Muenke syndrome	FGFR3	1	Link
n/a	Hypochondroplasia	FGFR3	1	Link
n/a	Achondroplasia	FGFR3	1	Link
	Colorectal cancer	FGFR3	1	Link
n/a	Thanatophoric dysplasia	FGFR3	1	Link
	Polycythemia vera	JAK2	4	Link
n/a	Myeloproliferative disorder	JAK2	4	Link
	Thrombocythemia	JAK2	4	Link
	Myelofibrosis	JAK2	4	Link
n/a	Budd-Chiari syndrome	JAK2	4	Link
n/a	Leishmaniasis	JAK2	4	Link
n/a	Type I diabetes mellitus	PRKCQ	8	Link
n/a	CATSHL syndrome	FGFR3	1	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	1	Link
	Apert syndrome	FGFR2	4	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	4	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	4	Link
	LEOPARD syndrome	RAF1	2	Link
	Noonan syndrome	RAF1	2	Link
	Kallmann syndrome	FGFR1	1	Link
	Bent bone dysplasia syndrome	FGFR2	4	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	4	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	4	Link
n/a	Multiple myeloma	FGFR3	1	Link
	Scaphocephaly	FGFR2	4	Link
n/a	Saethre-Chotzen syndrome	FGFR2	4	Link
	Craniosynostosis	FGFR2	4	Link
n/a	Alcoholism	RAF1	2	Link
n/a	Amoebiasis	PTK2	4	Link

BioXGEM.

KIDFamMap

Allelic Variants