KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2XB7A_GUI (PDB code: 2XB7, chain A)
Number of involved diseases in the family	107
Number of TEC related diseases	1

All kinase in this family TEC

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Measles	FYN, JAK1, JAK2, JAK3, MAP3K7, TYK2	2	Link
	Prostate cancer	EGFR, EPHB2, FGFR1, FGFR2, IGF1R, INSRR	38	Link
n/a	Epstein-Barr virus infection	FGR, JAK1, JAK3, MAP3K7, SYK, TYK2	2	Link
n/a	Tuberculosis	JAK1, JAK2, SRC, SYK	2	Link
	Melanoma	EGFR, FGFR1, IGF1R, MET	39	Link
n/a	Herpes simplex infection	JAK1, JAK2, MAP3K7, TYK2	2	Link
n/a	Toxoplasmosis	JAK1, JAK2, MAP3K7, TYK2	2	Link
	Lung cancer	ALK, EGFR, PTK2, ROS1	10	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, MET, SRC	3	Link
n/a	Hepatitis C	EGFR, JAK1, TYK2	2	Link
	Leukemia	ABL1, ABL2, JAK2	2	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	2	Link
	Gastric cancer	EGFR, FGFR2, MET	3	Link
n/a	Leishmaniasis	JAK1, JAK2, MAP3K7	2	Link
	Neuroblastoma	ALK, NTRK1, NTRK2	10	Link
n/a	Influenza A	JAK1, JAK2, TYK2	2	Link
n/a	Cervical cancer	EGFR, FGFR3	1	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	2	Link
	Hemangioma	FLT4, KDR	2	Link
n/a	Immunodeficiencies	JAK3, ZAP70	20	Link
n/a	Bladder cancer	EGFR, FGFR3	1	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	2	Link
n/a	Shigellosis	ABL1, SRC	2	Link
	Colon cancer	AURKA, SRC	2	Link
	Pfeiffer syndrome	FGFR1, FGFR2	2	Link
n/a	Choriocarcinoma	CSF1R, EGFR	1	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	2	Link
	LADD syndrome	FGFR2, FGFR3	1	Link
	Crouzon syndrome	FGFR2, FGFR3	1	Link
n/a	Thyroid cancer	NTRK1, RET	2	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	1	Link
	Apert syndrome	FGFR2	1	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	1	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	1	Link
n/a	Multiple myeloma	FGFR3	1	Link
n/a	Saethre-Chotzen syndrome	FGFR2	1	Link
	Craniosynostosis	FGFR2	1	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	1	Link
	Scaphocephaly	FGFR2	1	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	1	Link
	Bent bone dysplasia syndrome	FGFR2	1	Link
	Cataract	EPHA2	1	Link
	Kallmann syndrome	FGFR1	2	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	1	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	1	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	1	Link
	Agammaglobulinemia	BTK	1	Link
n/a	Maturity onset diabetes of the young	BLK	1	Link
n/a	Agammaglobulinemias	BTK	1	Link
n/a	Pituitary Dwarfism	BTK	1	Link
n/a	Oral cancer	EGFR	1	Link
n/a	Esophageal cancer	EGFR	1	Link
	Osteoglophonic dysplasia	FGFR1	2	Link
	Trigonocephaly	FGFR1	2	Link
	Hypogonadotropic hypogonadism	FGFR1	2	Link
n/a	CATSHL syndrome	FGFR3	1	Link
n/a	Glioma	EGFR	1	Link
n/a	Laryngeal cancer	EGFR	1	Link
	Adenocarcinoma of lung	EGFR	1	Link
n/a	Spermatocytic seminoma	FGFR3	1	Link
n/a	Achondroplasia	FGFR3	1	Link
n/a	Congenital myasthenic syndrome	MUSK	1	Link
n/a	Myasthenic syndrome	MUSK	1	Link
n/a	Insensitivity to pain	NTRK1	1	Link
n/a	Alcoholism	NTRK2	2	Link
	Hepatocellular carcinoma	MET	3	Link
n/a	Autism suseptibility	MET	3	Link
	Retinitis pigmentosa	MERTK	1	Link
	Renal cell carcinoma	MET	3	Link
n/a	Cholangiocarcinoma	MET	3	Link
n/a	Malaria	MET	3	Link
n/a	Obesity	NTRK2	2	Link
n/a	Amoebiasis	PTK2	1	Link
	Renal agenesis	RET	2	Link
n/a	Transient erythroblastopenia of childhood	TEC	1	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	2	Link
	Selective T-cell defect	ZAP70	20	Link
	Pheochromocytoma	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
n/a	46XY sex reversal 6	MAP3K1	1	Link
	SCID	JAK3	1	Link
n/a	Lymphedemas	FLT4	1	Link
n/a	Lymphedema	FLT4	1	Link
n/a	Prion diseases	FYN	1	Link
n/a	Malignant pleural mesothelioma	IGF1R	37	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Thanatophoric dysplasia	FGFR3	1	Link
	Colorectal cancer	FGFR3	1	Link
n/a	Hypochondroplasia	FGFR3	1	Link
n/a	Muenke syndrome	FGFR3	1	Link
n/a	Nevus	FGFR3	1	Link
n/a	Synovial sarcoma	IGF1R	37	Link
	Insulin-like growth factor I	IGF1R	37	Link
n/a	Budd-Chiari syndrome	JAK2	2	Link
	Myelofibrosis	JAK2	2	Link
n/a	Myeloproliferative disorder	JAK2	2	Link
	Thrombocythemia	JAK2	2	Link
	Polycythemia vera	JAK2	2	Link
	Lymphoproliferative syndrome	ITK	1	Link
n/a	Leprechaunism	INSR	11	Link
	Rabson-Mendenhall syndrome	INSR	11	Link
	Diabetes mellitus	INSR	11	Link
	Hyperinsulinemic hypoglycemia	INSR	11	Link

BioXGEM.

KIDFamMap

Allelic Variants