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Example2
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
1P5
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
JAK2 (PDB code: 3IO7)
[PDB]
[PDBsum]
Inhibitor
CP_690550 (HET code: 1P5)
[PDB]
Summary of KIF 3IO7A_1P5
(JAK2, PDB code:
3IO7
, chain A)
Number of family interactions
107
Number of family kinase
24 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
65 (6 are GSK3A inhibitors)
Involved diseases
60 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
GSK3A and 6 inhibitors