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Example2
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
SU2
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
FGFR1 (PDB code: 1AGW)
[PDB]
[PDBsum]
Inhibitor
SU 4984 (HET code: SU2)
[PDB]
Summary of KIF 1AGWA_SU2
(FGFR1, PDB code:
1AGW
, chain A)
Number of family interactions
188
Number of family kinase
77 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
81 (1 are MELK inhibitors)
Involved diseases
111 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
MELK and 1 inhibitors