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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
T3M
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
NEK2 (PDB code: 2XKD)
[PDB]
[PDBsum]
Inhibitor
4-[3-Amino-6-(3,4,5-Trimethoxyphenyl)pyrazin-2-Yl]benzoic Acid (HET code: T3M)
[PDB]
Summary of KIF 2XKDA_T3M
(NEK2, PDB code:
2XKD
, chain A)
Number of family interactions
45
Number of family kinase
4 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
38 (2 are NEK1 inhibitors)
Involved diseases
5 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
NEK1 and 2 inhibitors