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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
WI2
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
NEK2 (PDB code: 2XKE)
[PDB]
[PDBsum]
Inhibitor
1-[3-Amino-6-(3-Methoxyphenyl)pyrazin-2-Yl]piperidine-4-Carboxylic Acid (HET code: WI2)
[PDB]
Summary of KIF 2XKEA_WI2
(NEK2, PDB code:
2XKE
, chain A)
Number of family interactions
23
Number of family kinase
2 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
21 (2 are NEK1 inhibitors)
Involved diseases
1 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
NEK1 and 2 inhibitors