Protein Surface  Ribbon
Inhibitor ED8
  ATP Location
Pocket ATP NLP HAP CLP SP
Selected template
Kinase NEK2 (PDB code: 2XNO) [PDB] [PDBsum]
Inhibitor 5-{6-[(1-Methylpiperidin-4-Yl)oxy]-1h-Benzimidazol-1-Yl}-3-{[2-(Trifluoromethyl)benzyl]oxy}thiophene-2-Carboxamide (HET code: ED8) [PDB]
 
Summary of KIF 2XNOA_ED8 (NEK2, PDB code: 2XNO, chain A)
Number of family interactions 122
Number of family kinase 12 (sequence conservation) (profiling results)
Number of family inhibitors 82 (15 are NEK2 inhibitors)
Involved diseases 9 (show)
Number of family anchors  
All kinase-inhibitor interactions in this family  NEK2 and 15 inhibitors