Protein Surface  Ribbon
Inhibitor GS2
  ATP Location
Pocket ATP NLP HAP CLP SP
Selected template
Kinase INSR (PDB code: 3EKK) [PDB] [PDBsum]
Inhibitor pyrrolo[2,3-d]pyrimidine deriv., 40 (HET code: GS2) [PDB]
 
Summary of KIF 3EKKA_GS2 (INSR, PDB code: 3EKK, chain A)
Number of family interactions 187
Number of family kinase 33 (sequence conservation) (profiling results)
Number of family inhibitors 131 (1 are ROS1 inhibitors)
Involved diseases 65 (show)
Number of family anchors  
All kinase-inhibitor interactions in this family  ROS1 and 1 inhibitors