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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ZZL
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
AURKA (PDB code: 2X81)
[PDB]
[PDBsum]
Inhibitor
MLN8054 (HET code: ZZL)
[PDB]
Summary of KIF 2X81A_ZZL
(AURKA, PDB code:
2X81
, chain A)
Number of family interactions
112
Number of family kinase
22 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
24 (2 are TNK1 inhibitors)
Involved diseases
64 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
TNK1 and 2 inhibitors