BioXGEM.
KIDFamMap
Home
Example1
Example2
Statistics
Document
Contact US
Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
S22
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
TTK (PDB code: 3GFW)
[PDB]
[PDBsum]
Inhibitor
1-(4-(4-(2-(Isopropylsulfonyl)phenylamino)-1H-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol (HET code: S22)
[PDB]
Summary of KIF 3GFWA_S22
(TTK, PDB code:
3GFW
, chain A)
Number of family interactions
42
Number of family kinase
21 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
4 (4 are TTK inhibitors)
Involved diseases
18 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
TTK and 4 inhibitors