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KIDFamMap
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
4 CASK related diseases
H00894
FG syndrome (FGS)
300422
FG syndrome 4
300749
Mental retardation and microcephaly with pontine and cerebellar hypoplasia
300422
Mental retardation, with or without nystagmus
Summary of query kinase
Query kinase
CASK (
O14936
)
Kinase group
CAMK
Number of conformation types
1
Number of structural templates
6 (
Total 15 inhibitors
)
Number of CASK related diseases
4 (
H00894
300422
300749
300422
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
6
3C0HA_AMP
(CASK)
CAMK
Adenosine mo...
I
13
7
25
A
3C0HA_AMP
(CASK)
CAMK
Adenosine mo...
I
13
7
25
13
7
25
A
3MFRA_ANP
(CASK)
CAMK
Phosphoamino...
I
13
5
25
13
5
25
A
3MFSA_ANP
(CASK)
CAMK
Phosphoamino...
I
13
5
25
13
5
25
A
3MFUA_ANP
(CASK)
CAMK
Phosphoamino...
I
13
5
25
13
5
25
A
3C0GA_3AM
(CASK)
CAMK
5'-adenylic ...
I
4
3
4
4
3
4
A
3C0IA_3AM
(CASK)
CAMK
5'-adenylic ...
I
4
3
4
4
3
4