BioXGEM.
KIDFamMap
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
4 BMPR1A related diseases
H01023
Juvenile polyposis syndrome
174900
Juvenile polyposis syndrome, infantile form
610069
Polyposis syndrome, hereditary mixed, 2
174900
Polyposis, juvenile intestinal
Summary of query kinase
Query kinase
BMPR1A (
P36894
)
Kinase group
TKL
Number of conformation types
0
Number of structural templates
11 (
Total 10 inhibitors
)
Number of BMPR1A related diseases
4 (
H01023
174900
610069
174900
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
11
1BYGA_STU
(CSK)
TKL
staurosporine
I
85
72
123
A
1BYGA_STU
(CSK)
TKL
staurosporine
I
85
72
123
85
72
123
A
1QPDA_STU
(LCK)
TKL
staurosporine
I
115
76
126
115
76
126
A
1QPJA_STU
(LCK)
TKL
staurosporine
I
115
76
126
115
76
126
A
2DQ7X_STU
(FYN)
TKL
staurosporine
I
91
74
124
91
74
124
A
2HZ4A_4ST
(ABL1)
TKL
staurosporine
I
159
103
156
159
103
156
A
3CKXA_STU
(STK24)
TKL
staurosporine
I
176
104
141
176
104
141
A
2FO0A_P16
(ABL1)
TKL
PD166326
I
89
70
123
89
70
123
A
2G2HA_P16
(ABL1)
TKL
PD166326
I
89
70
123
89
70
123
A
2HZIA_JIN
(ABL1)
TKL
PD180970
I
90
77
120
90
77
120
A
2GQGA_1N1
(ABL1)
TKL
Dasatinib
I
74
32
117
74
32
117
A
1OPLA_P16
(ABL1)
TKL
PD166326
I
89
70
123
89
70
123