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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
1 DYRK1A related diseases
614104
Mental retardation, autosomal dominant 7
Summary of query kinase
Query kinase
DYRK1A (
Q13627
)
Kinase group
CMGC
Number of conformation types
1
Number of structural templates
4 (
Total 101 inhibitors
)
Number of DYRK1A related diseases
1 (
614104
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
4
3ANRA_HRM
(DYRK1A)
CMGC
HARMINE
I
8
13
18
A
3ANRA_HRM
(DYRK1A)
CMGC
HARMINE
I
8
13
18
8
13
18
A
3ANQA_EHB
(DYRK1A)
CMGC
TG003
I
7
3
2
7
3
2
A
2VX3A_D15
(DYRK1A)
CMGC
pyrazole-3-y...
I
5
19
18
5
19
18
A
2WO6A_D15
(DYRK1A)
CMGC
pyrazole-3-y...
I
5
19
18
5
19
18