BioXGEM.
KIDFamMap
Home
Example1
Example2
Statistics
Document
Contact US
Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
2 ZAP70 related diseases
H00093
Combined immunodeficiencies (CIDs)
OMIM
(176947)
Selective T-cell defect
Summary of query kinase
Query kinase
ZAP70 (
P43403
)
Kinase group
TK
Number of conformation types
2
Number of structural templates
2 (
Total 169 inhibitors
)
Number of ZAP70 related diseases
2 (
H00093
OMIM:176947
)
Number of allelic variants
2 (
R465H
S518R
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
1
1U59A_STU
(ZAP70)
TK
staurosporine
I
96
80
114
A
1U59A_STU
(ZAP70)
TK
staurosporine
I
96
80
114
96
80
114
B
1
2OZOA_ANP
(ZAP70)
TK
Phosphoamino...
I
17
11
57
B
2OZOA_ANP
(ZAP70)
TK
Phosphoamino...
I
17
11
57
17
11
57