KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2XNEA_ASH (PDB code: 2XNE, chain A)
Number of involved diseases in the family	70
Number of AURKA related diseases	1

All kinase in this family AURKA

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Herpes simplex infection	CDC2, CDK2, JAK2, MAPK10, MAPK9	25	Link
	Prostate cancer	BRAF, CDK2, EGFR, FGFR2	11	Link
n/a	Influenza A	IRAK4, JAK2, MAPK10, MAPK9	16	Link
	Lung cancer	BRAF, CDK2, CDK4, EGFR	12	Link
n/a	Tuberculosis	IRAK4, JAK2, MAPK10, MAPK9	16	Link
n/a	Toxoplasmosis	IRAK4, JAK2, MAPK10, MAPK9	16	Link
	Leukemia	ABL1, BRAF, CDK4, JAK2	12	Link
n/a	Measles	CDK2, CDK4, IRAK4, JAK2	11	Link
n/a	Epstein-Barr virus infection	CDC2, CDK2, MAPK10, MAPK9	20	Link
n/a	Hepatitis C	BRAF, EGFR, MAPK10, MAPK9	17	Link
n/a	Pertussis	IRAK4, MAPK10, MAPK9	12	Link
n/a	Shigellosis	ABL1, MAPK10, MAPK9	12	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, MAPK10, MAPK9	14	Link
n/a	Chagas disease	IRAK4, MAPK10, MAPK9	12	Link
	Melanoma	BRAF, CDK4, EGFR	9	Link
n/a	Glioma	CDK4, EGFR	6	Link
n/a	Thyroid cancer	BRAF, RET	4	Link
n/a	Cervical cancer	CDK4, EGFR	6	Link
n/a	Leishmaniasis	IRAK4, JAK2	5	Link
	Adenocarcinoma of lung	BRAF, EGFR	6	Link
n/a	Malignant melanoma	BRAF, CDK4	6	Link
n/a	Salmonella infection	MAPK10, MAPK9	11	Link
	Diabetes mellitus	MAPK10, MAPK9	11	Link
	Gastric cancer	EGFR, FGFR2	3	Link
n/a	Bladder cancer	EGFR	3	Link
n/a	Laryngeal cancer	EGFR	3	Link
n/a	Esophageal cancer	EGFR	3	Link
n/a	Oral cancer	EGFR	3	Link
n/a	Choriocarcinoma	EGFR	3	Link
n/a	Alcoholism	BRAF	3	Link
n/a	Viral myocarditis	ABL1	1	Link
	LEOPARD syndrome	BRAF	3	Link
	Colorectal cancer	BRAF	3	Link
	Cardiofaciocutaneous syndrome	BRAF	3	Link
n/a	Noonan syndrome and related disorders	BRAF	3	Link
	Noonan syndrome	BRAF	3	Link
	Colon cancer	AURKA	6	Link
n/a	Pathogenic Escherichia coli infection	ABL1	1	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	2	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	2	Link
	Apert syndrome	FGFR2	2	Link
n/a	Epileptic encephalopathy	MAPK10	10	Link
n/a	Early infantile epileptic encephalopathy	MAPK10	10	Link
	SCID	LCK	4	Link
	Thrombocythemia	JAK2	5	Link
n/a	Immunodeficiencies	LCK	4	Link
n/a	Renal agenesis and Renal adysplasia	RET	1	Link
	Hirschsprung disease	RET	1	Link
	Pheochromocytoma	RET	1	Link
	Renal agenesis	RET	1	Link
	Multiple endocrine neoplasia	RET	1	Link
n/a	Medullary thyroid carcinoma	RET	1	Link
n/a	Congenital central hypoventilation syndrome	RET	1	Link
	Central hypoventilation syndrome	RET	1	Link
n/a	Myeloproliferative disorder	JAK2	5	Link
	Myelofibrosis	JAK2	5	Link
	Jackson-Weiss syndrome	FGFR2	2	Link
	LADD syndrome	FGFR2	2	Link
	Crouzon syndrome	FGFR2	2	Link
	Craniosynostosis	FGFR2	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	2	Link
	Bent bone dysplasia syndrome	FGFR2	2	Link
	Pfeiffer syndrome	FGFR2	2	Link
n/a	Saethre-Chotzen syndrome	FGFR2	2	Link
	Polycythemia vera	JAK2	5	Link
n/a	Budd-Chiari syndrome	JAK2	5	Link
	IRAK4 deficiency	IRAK4	1	Link
n/a	Invasive pneumococcal disease	IRAK4	1	Link
	Scaphocephaly	FGFR2	2	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	2	Link

BioXGEM.

KIDFamMap

Allelic Variants