KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3EZRA_EZR (PDB code: 3EZR, chain A)
Number of involved diseases in the family	62
Number of CDK2 related diseases	5

All kinase in this family CDK2

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Measles	AKT1, AKT2, CDK2, CDK4, FYN, GSK3B, IRAK4, JAK1, JAK2, JAK3	58	Link
n/a	Epstein-Barr virus infection	AKT1, AKT2, CDC2, CDK2, GSK3B, JAK1, JAK3, LYN, MAPK14	56	Link
n/a	Influenza A	AKT1, AKT2, GSK3B, IRAK4, JAK1, JAK2, MAPK14, PRKCA, PRKCB	36	Link
n/a	Tuberculosis	AKT1, AKT2, IRAK4, JAK1, JAK2, MAPK14, SRC	67	Link
n/a	Toxoplasmosis	AKT1, AKT2, IRAK4, JAK1, JAK2, MAPK14	28	Link
	Leukemia	ABL1, AKT1, AKT2, CDK4, JAK2, RPS6KB1	40	Link
n/a	Hepatitis C	AKT1, AKT2, GSK3B, JAK1, MAPK14	29	Link
	Melanoma	AKT1, AKT2, CDK4, FGFR1, MET	39	Link
n/a	Leishmaniasis	IRAK4, JAK1, JAK2, MAPK14, PRKCB	8	Link
	Prostate cancer	AKT1, AKT2, CDK2, FGFR1, GSK3B	58	Link
n/a	Chagas disease	AKT1, AKT2, IRAK4, MAPK14	24	Link
	Lung cancer	AKT1, AKT2, CDK2, CDK4	43	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	LYN, MAPK14, MET, SRC	41	Link
n/a	Herpes simplex infection	CDC2, CDK2, JAK1, JAK2	30	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA	16	Link
n/a	Immunodeficiencies	JAK3, LCK, ZAP70	26	Link
n/a	Shigellosis	ABL1, MAPK14, SRC	50	Link
n/a	Pertussis	IRAK4, MAPK14	4	Link
	Colon cancer	AURKA, SRC	42	Link
	Ovarian cancer	AKT1, AKT2	20	Link
n/a	African trypanosomiasis	PRKCA, PRKCB	3	Link
n/a	Amoebiasis	PRKCA, PRKCB	3	Link
n/a	Vibrio cholerae infection	PRKCA, PRKCB	3	Link
	SCID	JAK3, LCK	17	Link
n/a	Viral myocarditis	ABL1, FYN	14	Link
	Hypoinsulinemic hypoglycemia	AKT2	18	Link
n/a	PTEN hamartoma tumor syndrome	AKT1	20	Link
n/a	Maturity onset diabetes of the young	BLK	3	Link
n/a	Familial partial lipodystrophy	AKT2	18	Link
	Diabetes mellitus	AKT2	18	Link
	Breast cancer	AKT1	20	Link
	Colorectal cancer	AKT1	20	Link
n/a	Cervical cancer	CDK4	4	Link
n/a	Schizophrenia	AKT1	20	Link
n/a	Proteus syndrome	AKT1	20	Link
	Osteoglophonic dysplasia	FGFR1	13	Link
n/a	Malignant melanoma	CDK4	4	Link
	Gastric cancer	MET	2	Link
n/a	Salmonella infection	MAPK14	1	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	1	Link
	Thrombocythemia	JAK2	4	Link
	Renal cell carcinoma	MET	2	Link
n/a	Cholangiocarcinoma	MET	2	Link
	Selective T-cell defect	ZAP70	11	Link
n/a	Pituitary tumor	PRKCA	3	Link
	Hepatocellular carcinoma	MET	2	Link
n/a	Malaria	MET	2	Link
n/a	Autism suseptibility	MET	2	Link
n/a	Myeloproliferative disorder	JAK2	4	Link
	Myelofibrosis	JAK2	4	Link
	Kallmann syndrome	FGFR1	13	Link
	Jackson-Weiss syndrome	FGFR1	13	Link
	Trigonocephaly	FGFR1	13	Link
n/a	Glioma	CDK4	4	Link
	Hypogonadotropic hypogonadism	FGFR1	13	Link
	Pfeiffer syndrome	FGFR1	13	Link
n/a	Prion diseases	FYN	4	Link
n/a	Budd-Chiari syndrome	JAK2	4	Link
	Polycythemia vera	JAK2	4	Link
	IRAK4 deficiency	IRAK4	3	Link
n/a	Basal cell carcinoma	GSK3B	6	Link
n/a	Invasive pneumococcal disease	IRAK4	3	Link

BioXGEM.

KIDFamMap

Allelic Variants