KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1R78A_FMD (PDB code: 1R78, chain A)
Number of involved diseases in the family	97
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	CDK2, CHUK, CSNK2A1, CSNK2A2, EIF2AK2, FGR, JAK1, JAK3, LYN, MAP2K3, MAP2K6, MAP3K7, MAPK10, MAPK9	23	Link
n/a	Measles	CDK2, CDK4, CHUK, CSNK2A1, CSNK2A2, EIF2AK2, FYN, IRAK4, JAK1, JAK2, JAK3, MAP3K7, PRKCQ	23	Link
n/a	Herpes simplex infection	CDK2, CHUK, CSNK2A1, CSNK2A2, EIF2AK2, JAK1, JAK2, MAP3K7, MAPK10, MAPK9	23	Link
n/a	Influenza A	EIF2AK2, IRAK4, JAK1, JAK2, MAP2K1, MAP2K3, MAP2K6, MAPK10, MAPK9	2	Link
n/a	Toxoplasmosis	CHUK, IRAK4, JAK1, JAK2, MAP2K3, MAP2K6, MAP3K7, MAPK10, MAPK9	2	Link
n/a	Tuberculosis	CAMK2A, CAMK2B, CAMK2D, IRAK4, JAK1, JAK2, MAPK10, MAPK9, SRC	2	Link
n/a	Shigellosis	ABL1, CHUK, MAPK10, MAPK9, ROCK1, ROCK2, SRC	2	Link
	Prostate cancer	CDK2, CHEK2, CHUK, FGFR1, FGFR2, MAP2K1, PDPK1	23	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CHUK, LYN, MAPK10, MAPK9, MET, SRC	2	Link
n/a	Salmonella infection	MAPK10, MAPK9, PKN1, PKN2, ROCK1, ROCK2	2	Link
	Leukemia	ABL1, CDK4, CHUK, JAK2, MAP2K1, RPS6KB1	2	Link
n/a	Hepatitis C	CHUK, EIF2AK2, JAK1, MAPK10, MAPK9	2	Link
	Melanoma	CDK4, FGFR1, MAP2K1, MET	2	Link
n/a	Chagas disease	CHUK, IRAK4, MAPK10, MAPK9	1	Link
n/a	Leishmaniasis	IRAK4, JAK1, JAK2, MAP3K7	2	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, ROCK1, ROCK2	2	Link
n/a	Alcoholism	CAMKK1, CAMKK2, MAP2K1, NTRK2	2	Link
	Lung cancer	CDK2, CDK4, CHUK	22	Link
n/a	Pertussis	IRAK4, MAPK10, MAPK9	1	Link
	Mental retardation	DYRK1A, PAK3, RPS6KA3	2	Link
	LADD syndrome	FGFR2, FGFR3	2	Link
n/a	Prion diseases	FYN, MAP2K1	2	Link
	Pfeiffer syndrome	FGFR1, FGFR2	2	Link
n/a	Bladder cancer	DAPK1, FGFR3	2	Link
	Gastric cancer	FGFR2, MET	2	Link
	SCID	JAK3, LCK	2	Link
n/a	Cervical cancer	CDK4, FGFR3	2	Link
	Neuroblastoma	NTRK2, NTRK3	2	Link
n/a	Viral myocarditis	ABL1, FYN	2	Link
n/a	Immunodeficiencies	JAK3, LCK	2	Link
	Diabetes mellitus	MAPK10, MAPK9	1	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	2	Link
	Crouzon syndrome	FGFR2, FGFR3	2	Link
n/a	Amyotrophic lateral sclerosis	MAP2K3, MAP2K6	2	Link
n/a	Non-syndromic X-linked mental retardation	PAK3, RPS6KA3	2	Link
	Kallmann syndrome	FGFR1	2	Link
	Craniosynostosis	FGFR2	2	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	2	Link
	Bent bone dysplasia syndrome	FGFR2	2	Link
	Apert syndrome	FGFR2	2	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	2	Link
n/a	Cocoon syndrome	CHUK	1	Link
	Trigonocephaly	FGFR1	2	Link
	Li-Fraumeni syndrome	CHEK2	1	Link
n/a	Glioma	CDK4	1	Link
n/a	Malignant melanoma	CDK4	1	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
	Breast cancer	CHEK2	1	Link
	Osteosarcoma	CHEK2	1	Link
	Osteoglophonic dysplasia	FGFR1	2	Link
	Hypogonadotropic hypogonadism	FGFR1	2	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	1	Link
n/a	Legionellosis	CLK1	2	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	2	Link
n/a	Saethre-Chotzen syndrome	FGFR2	2	Link
	Renal cell carcinoma	MET	1	Link
n/a	Cholangiocarcinoma	MET	1	Link
n/a	Malaria	MET	1	Link
n/a	Epileptic encephalopathy	MAPK10	1	Link
n/a	Early infantile epileptic encephalopathy	MAPK10	1	Link
	Thrombocythemia	JAK2	2	Link
n/a	Noonan syndrome and related disorders	MAP2K1	2	Link
	Cardiofaciocutaneous syndrome	MAP2K1	2	Link
n/a	Autism suseptibility	MET	1	Link
	Hepatocellular carcinoma	MET	1	Link
n/a	Type I diabetes mellitus	PRKCQ	2	Link
n/a	Coffin-Lowry syndrome	RPS6KA3	2	Link
	Colon cancer	SRC	2	Link
	Glycogen storage disease	PHKG2	2	Link
n/a	Cirrhosis due to liver phosphorylase kinase deficiency	PHKG2	2	Link
n/a	Congenital myasthenic syndrome	MUSK	2	Link
n/a	Myasthenic syndrome	MUSK	2	Link
n/a	Obesity	NTRK2	2	Link
n/a	Glycogen storage diseases	PHKG2	2	Link
n/a	Myeloproliferative disorder	JAK2	2	Link
	Myelofibrosis	JAK2	2	Link
n/a	Hypochondroplasia	FGFR3	2	Link
n/a	Muenke syndrome	FGFR3	2	Link
n/a	Nevus	FGFR3	2	Link
	Colorectal cancer	FGFR3	2	Link
n/a	Achondroplasia	FGFR3	2	Link
	Scaphocephaly	FGFR2	2	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	2	Link
n/a	Multiple myeloma	FGFR3	2	Link
n/a	CATSHL syndrome	FGFR3	2	Link
n/a	Spermatocytic seminoma	FGFR3	2	Link
n/a	Thanatophoric dysplasia	FGFR3	2	Link
	Lymphoproliferative syndrome	ITK	2	Link
	Polycythemia vera	JAK2	2	Link
n/a	Budd-Chiari syndrome	JAK2	2	Link
	IRAK4 deficiency	IRAK4	1	Link
n/a	Invasive pneumococcal disease	IRAK4	1	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Congenital stationary night blindness	GRK1	1	Link
n/a	Oguchi disease	GRK1	1	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	1	Link

BioXGEM.

KIDFamMap

Allelic Variants