KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1XBCA_STU (PDB code: 1XBC, chain A)
Number of involved diseases in the family	105
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	FGR, JAK1, JAK3, LYN, PRKACG, SYK, TYK2	16	Link
	Prostate cancer	CHEK2, EGFR, EPHB2, FGFR1, FGFR2, PDGFRA, PDGFRB	42	Link
n/a	Measles	FYN, JAK1, JAK2, JAK3, TYK2	16	Link
	Leukemia	ABL1, ABL2, JAK2, KIT, PDGFRB	15	Link
	Lung cancer	ALK, EGFR, PTK2, ROS1	40	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, SRC	41	Link
n/a	Tuberculosis	JAK1, JAK2, SRC, SYK	21	Link
	Melanoma	EGFR, FGFR1, PDGFRA, PDGFRB	41	Link
n/a	Influenza A	JAK1, JAK2, PRKCA, TYK2	59	Link
n/a	Amoebiasis	PRKACG, PRKCA, PTK2	57	Link
n/a	Herpes simplex infection	JAK1, JAK2, TYK2	10	Link
n/a	Immunodeficiencies	JAK3, LCK, ZAP70	16	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	41	Link
n/a	Toxoplasmosis	JAK1, JAK2, TYK2	10	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA	61	Link
	Neuroblastoma	ALK, NTRK2, NTRK3	10	Link
n/a	Hepatitis C	EGFR, JAK1, TYK2	40	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	12	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	12	Link
n/a	Prion diseases	FYN, PRKACG	10	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
n/a	Leishmaniasis	JAK1, JAK2	10	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	SCID	JAK3, LCK	16	Link
	Gastric cancer	EGFR, FGFR2	39	Link
n/a	Vibrio cholerae infection	PRKACG, PRKCA	55	Link
n/a	Choriocarcinoma	CSF1R, EGFR	43	Link
n/a	Shigellosis	ABL1, SRC	20	Link
n/a	Cervical cancer	EGFR, FGFR3	38	Link
n/a	Bladder cancer	EGFR, FGFR3	38	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
	Agammaglobulinemia	BTK	5	Link
n/a	Pituitary Dwarfism	BTK	5	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
	Scaphocephaly	FGFR2	8	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
n/a	Agammaglobulinemias	BTK	5	Link
	Craniosynostosis	FGFR2	8	Link
	Li-Fraumeni syndrome	CHEK2	5	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
	Adenocarcinoma of lung	EGFR	38	Link
	Trigonocephaly	FGFR1	9	Link
n/a	Oral cancer	EGFR	38	Link
n/a	Laryngeal cancer	EGFR	38	Link
	Kallmann syndrome	FGFR1	9	Link
	Breast cancer	CHEK2	5	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	13	Link
	Osteosarcoma	CHEK2	5	Link
n/a	Nevus	FGFR3	7	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	African trypanosomiasis	PRKCA	55	Link
n/a	Pituitary tumor	PRKCA	55	Link
n/a	Thyroid cancer	RET	11	Link
n/a	Cardiomyopathy	PRKACG	1	Link
n/a	Cocaine addiction	PRKACG	1	Link
n/a	Myasthenic syndrome	MUSK	5	Link
n/a	Alcoholism	NTRK2	9	Link
n/a	Obesity	NTRK2	9	Link
n/a	Hypereosinophilic syndrome	PDGFRA	10	Link
n/a	Renal agenesis and Renal adysplasia	RET	11	Link
	Hirschsprung disease	RET	11	Link
	Colon cancer	SRC	19	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	8	Link
	Selective T-cell defect	ZAP70	10	Link
	Renal agenesis	RET	11	Link
	Pheochromocytoma	RET	11	Link
n/a	Congenital central hypoventilation syndrome	RET	11	Link
	Central hypoventilation syndrome	RET	11	Link
n/a	Medullary thyroid carcinoma	RET	11	Link
	Multiple endocrine neoplasia	RET	11	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
	Mastocytosis with associated hematologic disorder	KIT	12	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
n/a	Achondroplasia	FGFR3	7	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Leprechaunism	INSR	5	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
	Thrombocythemia	JAK2	10	Link
	Piebaldism	KIT	12	Link
n/a	Germ cell tumors	KIT	12	Link
	Mast cell leukemia	KIT	12	Link
	Myelofibrosis	JAK2	10	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
	Diabetes mellitus	INSR	5	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
	Lymphoproliferative syndrome	ITK	6	Link
	Polycythemia vera	JAK2	10	Link

BioXGEM.

KIDFamMap

Allelic Variants