KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2BMCA_MPY (PDB code: 2BMC, chain A)
Number of involved diseases in the family	107
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	CDC2, CDK2, CSNK2A1, CSNK2A2, GSK3B, JAK1, JAK3, MAP2K4, MAPK10, MAPK8, RIPK1	21	Link
n/a	Measles	CDK2, CDK4, CSNK2A1, CSNK2A2, GSK3B, IRAK4, JAK1, JAK2, JAK3, PRKCQ	37	Link
n/a	Herpes simplex infection	CDC2, CDK2, CSNK2A1, CSNK2A2, JAK1, JAK2, MAPK10, MAPK8	15	Link
n/a	Influenza A	GSK3B, IRAK4, JAK1, JAK2, MAP2K4, MAPK10, MAPK8, RAF1	9	Link
n/a	Hepatitis C	EGFR, GSK3B, JAK1, MAPK10, MAPK8, RAF1, RIPK1	10	Link
n/a	Tuberculosis	CAMK2A, IRAK4, JAK1, JAK2, MAPK10, MAPK8, RAF1	3	Link
	Prostate cancer	CDK2, EGFR, FGFR1, FGFR2, GSK3B, PDPK1, RAF1	36	Link
	Leukemia	ABL1, ABL2, CDK4, JAK2, RAF1, RPS6KB1	26	Link
	Lung cancer	ALK, CDK2, CDK4, EGFR, PTK2	32	Link
n/a	Toxoplasmosis	IRAK4, JAK1, JAK2, MAPK10, MAPK8	2	Link
	Melanoma	CDK4, EGFR, FGFR1, RAF1	29	Link
n/a	Alcoholism	CAMKK1, CAMKK2, NTRK2, RAF1	2	Link
	Diabetes mellitus	MAPK10, MAPK8, PRKCD, PRKCZ	6	Link
n/a	Chagas disease	IRAK4, MAP2K4, MAPK10, MAPK8	1	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	3	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, MAP2K4, MAPK10, MAPK8	3	Link
n/a	Pertussis	IRAK4, MAPK10, MAPK8	1	Link
n/a	Salmonella infection	MAPK10, MAPK8, PKN2	1	Link
n/a	Cardiomyopathy	MYLK2, PRKAA1, PRKAA2	1	Link
n/a	Leishmaniasis	IRAK4, JAK1, JAK2	2	Link
n/a	Immunodeficiencies	JAK3, LCK, ZAP70	11	Link
n/a	Cervical cancer	CDK4, EGFR, FGFR3	23	Link
n/a	Shigellosis	ABL1, MAPK10, MAPK8	4	Link
	Gastric cancer	EGFR, FGFR2	3	Link
	Pfeiffer syndrome	FGFR1, FGFR2	6	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	6	Link
n/a	Viral myocarditis	ABL1, ABL2	4	Link
n/a	Thyroid cancer	NTRK1, RET	3	Link
n/a	Bladder cancer	EGFR, FGFR3	3	Link
	SCID	JAK3, LCK	11	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	3	Link
n/a	Glioma	CDK4, EGFR	23	Link
	LADD syndrome	FGFR2, FGFR3	2	Link
	Crouzon syndrome	FGFR2, FGFR3	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	1	Link
	Trigonocephaly	FGFR1	6	Link
	Bent bone dysplasia syndrome	FGFR2	1	Link
n/a	Pathogenic Escherichia coli infection	ABL1	4	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	1	Link
	Kallmann syndrome	FGFR1	6	Link
	Apert syndrome	FGFR2	1	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	1	Link
	Craniosynostosis	FGFR2	1	Link
	Colon cancer	AURKA	37	Link
	Osteoglophonic dysplasia	FGFR1	6	Link
n/a	Saethre-Chotzen syndrome	FGFR2	1	Link
n/a	Esophageal cancer	EGFR	2	Link
n/a	Oral cancer	EGFR	2	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	1	Link
n/a	Malignant melanoma	CDK4	21	Link
n/a	Cocaine addiction	CDK5	2	Link
n/a	Choriocarcinoma	EGFR	2	Link
n/a	Laryngeal cancer	EGFR	2	Link
n/a	Maturity onset diabetes of the young	BLK	1	Link
	Hypogonadotropic hypogonadism	FGFR1	6	Link
n/a	Agammaglobulinemias	BTK	1	Link
	Adenocarcinoma of lung	EGFR	2	Link
	Agammaglobulinemia	BTK	1	Link
n/a	Pituitary Dwarfism	BTK	1	Link
	Colorectal cancer	FGFR3	2	Link
	Scaphocephaly	FGFR2	1	Link
n/a	Cirrhosis due to liver phosphorylase kinase deficiency	PHKG2	1	Link
	Glycogen storage disease	PHKG2	1	Link
n/a	Type I diabetes mellitus	PRKCQ	2	Link
n/a	Amoebiasis	PTK2	1	Link
n/a	Glycogen storage diseases	PHKG2	1	Link
n/a	Obesity	NTRK2	1	Link
n/a	Epileptic encephalopathy	MAPK10	1	Link
n/a	Familial thoracic aortic aneurysm and dissection	MYLK	1	Link
n/a	Aortic aneurysm	MYLK	1	Link
n/a	Insensitivity to pain	NTRK1	2	Link
	LEOPARD syndrome	RAF1	1	Link
	Noonan syndrome	RAF1	1	Link
	Renal agenesis	RET	2	Link
	Venous malformations	TEK	2	Link
n/a	Rheumatoid arthritis	TEK	2	Link
	Selective T-cell defect	ZAP70	1	Link
	Pheochromocytoma	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
n/a	Early infantile epileptic encephalopathy	MAPK10	1	Link
	Thrombocythemia	JAK2	2	Link
n/a	Muenke syndrome	FGFR3	2	Link
n/a	Nevus	FGFR3	2	Link
n/a	Spermatocytic seminoma	FGFR3	2	Link
n/a	Thanatophoric dysplasia	FGFR3	2	Link
n/a	Hypochondroplasia	FGFR3	2	Link
n/a	Achondroplasia	FGFR3	2	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	1	Link
n/a	Multiple myeloma	FGFR3	2	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	2	Link
n/a	CATSHL syndrome	FGFR3	2	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Congenital stationary night blindness	GRK1	1	Link
	Polycythemia vera	JAK2	2	Link
n/a	Budd-Chiari syndrome	JAK2	2	Link
	Myelofibrosis	JAK2	2	Link
n/a	Myeloproliferative disorder	JAK2	2	Link
	Lymphoproliferative syndrome	ITK	5	Link
	IRAK4 deficiency	IRAK4	1	Link
n/a	Oguchi disease	GRK1	1	Link
n/a	Basal cell carcinoma	GSK3B	7	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	1	Link
n/a	Invasive pneumococcal disease	IRAK4	1	Link

BioXGEM.

KIDFamMap

Allelic Variants