KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2C6EA_HPM (PDB code: 2C6E, chain A)
Number of involved diseases in the family	90
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	CDK2, CHEK2, EGFR, FGFR1, FGFR2, RAF1	56	Link
n/a	Tuberculosis	JAK2, MAPK8, MAPK9, PLK3, RAF1	11	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, MAPK8, MAPK9	49	Link
	Leukemia	ABL1, JAK2, RAF1, RPS6KB1	9	Link
n/a	Influenza A	JAK2, MAPK8, MAPK9, RAF1	9	Link
n/a	Hepatitis C	EGFR, MAPK8, MAPK9, RAF1	50	Link
	Lung cancer	ALK, CDK2, EGFR, PTK2	53	Link
n/a	Measles	CDK2, JAK2, JAK3, PRKCQ	15	Link
n/a	Epstein-Barr virus infection	CDK2, JAK3, MAPK8, MAPK9	8	Link
n/a	Herpes simplex infection	CDK2, JAK2, MAPK8, MAPK9	8	Link
n/a	Toxoplasmosis	JAK2, MAPK8, MAPK9	7	Link
	Diabetes mellitus	MAPK8, MAPK9, PRKCD	11	Link
	Melanoma	EGFR, FGFR1, RAF1	48	Link
n/a	Shigellosis	ABL1, MAPK8, MAPK9	6	Link
n/a	Immunodeficiencies	JAK3, LCK	54	Link
	Pfeiffer syndrome	FGFR1, FGFR2	5	Link
	Crouzon syndrome	FGFR2, FGFR3	5	Link
	Gastric cancer	EGFR, FGFR2	49	Link
n/a	Bladder cancer	EGFR, FGFR3	45	Link
n/a	Cervical cancer	EGFR, FGFR3	45	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	5	Link
	LADD syndrome	FGFR2, FGFR3	5	Link
n/a	Chagas disease	MAPK8, MAPK9	3	Link
n/a	Pertussis	MAPK8, MAPK9	3	Link
	SCID	JAK3, LCK	54	Link
n/a	Salmonella infection	MAPK8, MAPK9	3	Link
n/a	Medullary thyroid carcinoma	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
n/a	Esophageal cancer	EGFR	45	Link
	Osteosarcoma	CHEK2	4	Link
n/a	Oral cancer	EGFR	45	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Choriocarcinoma	EGFR	45	Link
	Adenocarcinoma of lung	EGFR	45	Link
	Hypogonadotropic hypogonadism	FGFR1	1	Link
n/a	Thyroid cancer	RET	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
	Breast cancer	CHEK2	4	Link
n/a	Glioma	EGFR	45	Link
n/a	Laryngeal cancer	EGFR	45	Link
	Multiple endocrine neoplasia	RET	2	Link
	Li-Fraumeni syndrome	CHEK2	4	Link
	Neuroblastoma	ALK	4	Link
	Colon cancer	AURKA	102	Link
	Venous malformations	TEK	25	Link
n/a	Viral myocarditis	ABL1	3	Link
n/a	Pathogenic Escherichia coli infection	ABL1	3	Link
n/a	Rheumatoid arthritis	TEK	25	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
n/a	Agammaglobulinemias	BTK	4	Link
	Renal agenesis	RET	2	Link
	Pheochromocytoma	RET	2	Link
n/a	Basal cell carcinoma	STK36	2	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	4	Link
n/a	Pituitary Dwarfism	BTK	4	Link
	Agammaglobulinemia	BTK	4	Link
	Trigonocephaly	FGFR1	1	Link
	Osteoglophonic dysplasia	FGFR1	1	Link
n/a	Nevus	FGFR3	1	Link
n/a	Spermatocytic seminoma	FGFR3	1	Link
n/a	Muenke syndrome	FGFR3	1	Link
n/a	Hypochondroplasia	FGFR3	1	Link
n/a	Achondroplasia	FGFR3	1	Link
	Colorectal cancer	FGFR3	1	Link
n/a	Thanatophoric dysplasia	FGFR3	1	Link
	Polycythemia vera	JAK2	4	Link
n/a	Myeloproliferative disorder	JAK2	4	Link
	Thrombocythemia	JAK2	4	Link
	Myelofibrosis	JAK2	4	Link
n/a	Budd-Chiari syndrome	JAK2	4	Link
n/a	Leishmaniasis	JAK2	4	Link
n/a	Type I diabetes mellitus	PRKCQ	8	Link
n/a	CATSHL syndrome	FGFR3	1	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	1	Link
	Apert syndrome	FGFR2	4	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	4	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	4	Link
	LEOPARD syndrome	RAF1	2	Link
	Noonan syndrome	RAF1	2	Link
	Kallmann syndrome	FGFR1	1	Link
	Bent bone dysplasia syndrome	FGFR2	4	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	4	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	4	Link
n/a	Multiple myeloma	FGFR3	1	Link
	Scaphocephaly	FGFR2	4	Link
n/a	Saethre-Chotzen syndrome	FGFR2	4	Link
	Craniosynostosis	FGFR2	4	Link
n/a	Alcoholism	RAF1	2	Link
n/a	Amoebiasis	PTK2	4	Link

BioXGEM.

KIDFamMap

Allelic Variants