Allelic Variants

There are no related allelic variants
Related diseases of KIF 2F4JA_VX6 (PDB code: 2F4J, chain A)
Number of involved diseases in the family 134
Number of FGFR3 related diseases 14
All kinase in this family  FGFR3
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
n/aEpstein-Barr virus infectionCDC2, CDK2, FGR, JAK1, JAK3,
LYN, MAP3K7, MAPK14, PRKACA,
RIPK1, SYK, TYK2		20Link
n/aMeaslesCDK2, FYN, IRAK4, JAK1,
JAK2, JAK3, MAP3K7, PRKCQ,
TYK2		34Link
Prostate cancerCDK2, EPHB2, FGFR1, FGFR2,
IGF1R, INSRR, MAP2K1,
PDGFRA, PDGFRB		18Link
n/aTuberculosisIRAK4, JAK1, JAK2, MAPK14,
PLK3, SRC, SYK		28Link
LeukemiaABL1, ABL2, JAK2, KIT,
MAP2K1, PDGFRB, TGFBR1		17Link
n/aToxoplasmosisIRAK4, JAK1, JAK2, MAP3K7,
MAPK14, TYK2		16Link
n/aHerpes simplex infectionCDC2, CDK2, JAK1, JAK2,
MAP3K7, TYK2		25Link
n/aInfluenza AIRAK4, JAK1, JAK2, MAP2K1,
MAPK14, TYK2		16Link
MelanomaFGFR1, IGF1R, MAP2K1, MET,
PDGFRA, PDGFRB		7Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCSK, LYN, MAPK14, MET, SRC15Link
n/aLeishmaniasisIRAK4, JAK1, JAK2, MAP3K7,
MAPK14		16Link
n/aHepatitis CJAK1, MAPK14, RIPK1, TYK24Link
NeuroblastomaALK, NTRK1, NTRK2, NTRK35Link
n/aShigellosisABL1, MAPK14, SRC17Link
n/aCardiomyopathyPRKAA1, PRKAA2, PRKACA3Link
n/aChagas diseaseIRAK4, MAPK14, TGFBR13Link
n/aAlcoholismMAP2K1, NTRK2, PRKACA4Link
n/aSalmonella infectionMAPK14, PKN1, PKN24Link
n/aViral myocarditisABL1, ABL2, FYN5Link
n/aPrion diseasesFYN, MAP2K1, PRKACA3Link
Lung cancerALK, CDK2, ROS114Link
Gastrointestinal stromal tumorKIT, PDGFRA3Link
Pfeiffer syndromeFGFR1, FGFR22Link
Jackson-Weiss syndromeFGFR1, FGFR22Link
HemangiomaFLT4, KDR7Link
SCIDJAK3, LCK9Link
n/aImmunodeficienciesJAK3, LCK9Link
LADD syndromeFGFR2, FGFR32Link
n/aPertussisIRAK4, MAPK143Link
Diabetes mellitusINSR, PRKCD16Link
Crouzon syndromeFGFR2, FGFR32Link
n/aMyeloproliferative disorderJAK2, PDGFRB14Link
n/aPathogenic Escherichia coli infectionABL1, FYN5Link
Gastric cancerFGFR2, MET2Link
n/aThyroid cancerNTRK1, RET5Link
n/aMedullary thyroid carcinomaNTRK1, RET5Link
n/aType I diabetes mellitusERBB3, PRKCQ10Link
Colon cancerAURKA, SRC71Link
n/aCocaine addictionCDK5, PRKACA2Link
n/aGliomaPDGFRA, PDGFRB2Link
ScaphocephalyFGFR22Link
AgammaglobulinemiaBTK2Link
n/aSaethre-Chotzen syndromeFGFR22Link
n/aMaturity onset diabetes of the youngBLK2Link
n/aAgammaglobulinemia and isolated hormone deficiencyBTK2Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR22Link
n/aMultiple myelomaFGFR32Link
n/aPrader-Willi and Angelman syndromesCDKL51Link
n/aAchondroplasiaFGFR32Link
n/aCervical cancerFGFR32Link
Colorectal cancerFGFR32Link
n/aCATSHL syndromeFGFR32Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR32Link
n/aPituitary DwarfismBTK2Link
n/aAgammaglobulinemiasBTK2Link
n/aBladder cancerFGFR32Link
n/aChrondrodysplasiaBMPR1B1Link
Fibrodysplasia ossificans progressivaACVR12Link
n/aEarly infantile epileptic encephalopathyCDKL51Link
Kallmann syndromeFGFR12Link
n/aLeukoencephalopathy, diffuse hereditary, with spheroidsCSF1R2Link
n/aChoriocarcinomaCSF1R2Link
n/aSpondylometaepiphyseal dysplasiaDDR22Link
n/aHypochondroplasiaFGFR32Link
n/aLethal congenital contractural syndromeERBB31Link
Osteoglophonic dysplasiaFGFR12Link
TrigonocephalyFGFR12Link
BrachydactylyBMPR1B1Link
n/aEpileptic encephalopathyCDKL51Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR22Link
CraniosynostosisFGFR22Link
Hypogonadotropic hypogonadismFGFR12Link
n/aAngelman syndrome-likeCDKL51Link
Bent bone dysplasia syndromeFGFR22Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR22Link
Apert syndromeFGFR22Link
Beare-Stevenson cutis gyrata syndromeFGFR22Link
n/aMalignant pleural mesotheliomaIGF1R7Link
n/aMuenke syndromeFGFR32Link
n/aAmoebiasisPRKACA1Link
n/aRenal agenesis and Renal adysplasiaRET3Link
Hirschsprung diseaseRET3Link
Central hypoventilation syndromeRET3Link
n/aCongenital central hypoventilation syndromeRET3Link
n/aVibrio cholerae infectionPRKACA1Link
n/aHypereosinophilic syndromePDGFRA2Link
Hepatocellular carcinomaMET2Link
n/aCongenital myasthenic syndromeMUSK2Link
n/aMyasthenic syndromeMUSK2Link
n/aObesityNTRK23Link
n/aInsensitivity to painNTRK15Link
Multiple endocrine neoplasiaRET3Link
PheochromocytomaRET3Link
n/aRheumatoid arthritisTEK3Link
Loeys-Dietz syndromeTGFBR11Link
n/aFamilial thoracic aortic aneurysm and dissectionTGFBR11Link
n/aTyrosine kinase 2 deficiencyTYK21Link
Multiple self-healing squamous epitheliomaTGFBR11Link
Venous malformationsTEK3Link
n/aTransient erythroblastopenia of childhoodTEC1Link
Renal agenesisRET3Link
n/aPopliteal pterygium syndromeRIPK41Link
n/aNon-syndromic X-linked mental retardationRPS6KA32Link
Mental retardationRPS6KA32Link
n/aCoffin-Lowry syndromeRPS6KA32Link
n/aAutism suseptibilityMET2Link
n/aMalariaMET2Link
Insulin-like growth factor IIGF1R7Link
n/aLeprechaunismINSR7Link
Rabson-Mendenhall syndromeINSR7Link
n/aInvasive pneumococcal diseaseIRAK41Link
Hyperinsulinemic hypoglycemiaINSR7Link
n/aSynovial sarcomaIGF1R7Link
n/aLymphedemaFLT42Link
n/aNevusFGFR32Link
n/aSpermatocytic seminomaFGFR32Link
n/aThanatophoric dysplasiaFGFR32Link
n/aLymphedemasFLT42Link
n/aCancer progression/metastasisFGFR42Link
IRAK4 deficiencyIRAK41Link
Lymphoproliferative syndromeITK2Link
n/aNoonan syndrome and related disordersMAP2K12Link
Cardiofaciocutaneous syndromeMAP2K12Link
n/aAmyotrophic lateral sclerosisMAPK142Link
n/aCholangiocarcinomaMET2Link
Renal cell carcinomaMET2Link
Mastocytosis with associated hematologic disorderKIT3Link
Mast cell leukemiaKIT3Link
n/aBudd-Chiari syndromeJAK214Link
Polycythemia veraJAK214Link
MyelofibrosisJAK214Link
ThrombocythemiaJAK214Link
n/aGerm cell tumorsKIT3Link
PiebaldismKIT3Link