KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2VWUA_7X1 (PDB code: 2VWU, chain A)
Number of involved diseases in the family	111
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	EGFR, EPHB2, FGFR1, FGFR2, IGF1R, INSRR	94	Link
n/a	Tuberculosis	IRAK1, IRAK4, JAK2, SRC, SYK	186	Link
n/a	Measles	FYN, IRAK1, IRAK4, JAK2, TYK2	9	Link
n/a	Epstein-Barr virus infection	FGR, IRAK1, LYN, SYK, TYK2	10	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	14	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, SRC	261	Link
	Leukemia	ABL1, ABL2, JAK2, TGFBR1	26	Link
n/a	Toxoplasmosis	IRAK1, IRAK4, JAK2, TYK2	5	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	26	Link
	Melanoma	EGFR, FGFR1, IGF1R	94	Link
n/a	Leishmaniasis	IRAK1, IRAK4, JAK2	5	Link
n/a	Influenza A	IRAK4, JAK2, TYK2	5	Link
n/a	Chagas disease	IRAK1, IRAK4, TGFBR1	6	Link
n/a	Cervical cancer	EGFR, FGFR3	91	Link
	Hemangioma	FLT4, KDR	86	Link
n/a	Hepatitis C	EGFR, TYK2	91	Link
n/a	Pertussis	IRAK1, IRAK4	5	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	29	Link
	Pfeiffer syndrome	FGFR1, FGFR2	29	Link
n/a	Immunodeficiencies	LCK, ZAP70	19	Link
n/a	Herpes simplex infection	JAK2, TYK2	1	Link
n/a	Bladder cancer	EGFR, FGFR3	91	Link
n/a	Choriocarcinoma	CSF1R, EGFR	91	Link
	LADD syndrome	FGFR2, FGFR3	5	Link
	Lung cancer	ALK, EGFR	98	Link
n/a	Shigellosis	ABL1, SRC	186	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	26	Link
	Crouzon syndrome	FGFR2, FGFR3	5	Link
	Gastric cancer	EGFR, FGFR2	91	Link
n/a	Thyroid cancer	NTRK1, RET	9	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	9	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	5	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	5	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	5	Link
	Kallmann syndrome	FGFR1	29	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	5	Link
	Scaphocephaly	FGFR2	5	Link
	Bent bone dysplasia syndrome	FGFR2	5	Link
	Craniosynostosis	FGFR2	5	Link
	Trigonocephaly	FGFR1	29	Link
	Apert syndrome	FGFR2	5	Link
n/a	Saethre-Chotzen syndrome	FGFR2	5	Link
	Cataract	EPHA2	6	Link
	Osteoglophonic dysplasia	FGFR1	29	Link
	Agammaglobulinemia	BTK	6	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	6	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	7	Link
n/a	Pituitary Dwarfism	BTK	6	Link
n/a	Agammaglobulinemias	BTK	6	Link
	Fibrodysplasia ossificans progressiva	ACVR1	4	Link
n/a	Pancreatic cancer	ACVR1B	1	Link
n/a	Maturity onset diabetes of the young	BLK	9	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	5	Link
n/a	Oral cancer	EGFR	91	Link
n/a	Type I diabetes mellitus	ERBB3	4	Link
n/a	Lethal congenital contractural syndrome	ERBB3	4	Link
	Hypogonadotropic hypogonadism	FGFR1	29	Link
n/a	Multiple myeloma	FGFR3	4	Link
	Adenocarcinoma of lung	EGFR	91	Link
n/a	Esophageal cancer	EGFR	91	Link
n/a	Glioma	EGFR	91	Link
n/a	Laryngeal cancer	EGFR	91	Link
n/a	Nevus	FGFR3	4	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	4	Link
n/a	Renal agenesis and Renal adysplasia	RET	8	Link
	Hirschsprung disease	RET	8	Link
n/a	Congenital central hypoventilation syndrome	RET	8	Link
	Central hypoventilation syndrome	RET	8	Link
n/a	Obesity	NTRK2	2	Link
n/a	Alcoholism	NTRK2	2	Link
n/a	Myeloproliferative disorder	JAK2	1	Link
	Thrombocythemia	JAK2	1	Link
	SCID	LCK	19	Link
n/a	Insensitivity to pain	NTRK1	2	Link
	Multiple endocrine neoplasia	RET	8	Link
	Pheochromocytoma	RET	8	Link
n/a	Familial thoracic aortic aneurysm and dissection	TGFBR1	1	Link
	Multiple self-healing squamous epithelioma	TGFBR1	1	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	1	Link
	Selective T-cell defect	ZAP70	1	Link
	Loeys-Dietz syndrome	TGFBR1	1	Link
n/a	Rheumatoid arthritis	TEK	10	Link
	Renal agenesis	RET	8	Link
	Colon cancer	SRC	186	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Venous malformations	TEK	10	Link
	Myelofibrosis	JAK2	1	Link
n/a	Budd-Chiari syndrome	JAK2	1	Link
n/a	Thanatophoric dysplasia	FGFR3	4	Link
n/a	Cancer progression/metastasis	FGFR4	2	Link
n/a	Lymphedemas	FLT4	9	Link
n/a	Lymphedema	FLT4	9	Link
n/a	Spermatocytic seminoma	FGFR3	4	Link
n/a	Muenke syndrome	FGFR3	4	Link
n/a	CATSHL syndrome	FGFR3	4	Link
n/a	Achondroplasia	FGFR3	4	Link
	Colorectal cancer	FGFR3	4	Link
n/a	Hypochondroplasia	FGFR3	4	Link
n/a	Prion diseases	FYN	8	Link
n/a	Malignant pleural mesothelioma	IGF1R	1	Link
n/a	Invasive pneumococcal disease	IRAK4	5	Link
	IRAK4 deficiency	IRAK4	5	Link
	Lymphoproliferative syndrome	ITK	1	Link
	Polycythemia vera	JAK2	1	Link
n/a	Asthma susceptibility	IRAK3	2	Link
	Hyperinsulinemic hypoglycemia	INSR	6	Link
n/a	Synovial sarcoma	IGF1R	1	Link
	Insulin-like growth factor I	IGF1R	1	Link
n/a	Leprechaunism	INSR	6	Link
	Diabetes mellitus	INSR	6	Link
	Rabson-Mendenhall syndrome	INSR	6	Link

BioXGEM.

KIDFamMap

Allelic Variants