KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2WKMA_PFY (PDB code: 2WKM, chain A)
Number of involved diseases in the family	98
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Measles	IRAK1, IRAK4, JAK1, JAK2, JAK3, MAP3K7	6	Link
n/a	Toxoplasmosis	IRAK1, IRAK4, JAK1, JAK2, MAP3K7	6	Link
n/a	Leishmaniasis	IRAK1, IRAK4, JAK1, JAK2, MAP3K7	6	Link
n/a	Epstein-Barr virus infection	IRAK1, JAK1, JAK3, MAP3K7	6	Link
	Lung cancer	ALK, EGFR, PTK2, ROS1	17	Link
n/a	Tuberculosis	IRAK1, IRAK4, JAK1, JAK2	6	Link
	Prostate cancer	EGFR, FGFR1, FGFR2	17	Link
	Melanoma	EGFR, FGFR1, MET	22	Link
n/a	Influenza A	IRAK4, JAK1, JAK2	6	Link
	Gastric cancer	EGFR, FGFR2, MET	20	Link
n/a	Herpes simplex infection	JAK1, JAK2, MAP3K7	6	Link
	Neuroblastoma	ALK, NTRK2, NTRK3	7	Link
n/a	Hepatitis C	EGFR, JAK1	14	Link
n/a	Chagas disease	IRAK1, IRAK4	5	Link
	LADD syndrome	FGFR2, FGFR3	5	Link
	Hemangioma	FLT4, KDR	21	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
n/a	Pertussis	IRAK1, IRAK4	5	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	Crouzon syndrome	FGFR2, FGFR3	5	Link
n/a	Choriocarcinoma	CSF1R, EGFR	17	Link
n/a	Cervical cancer	EGFR, FGFR3	16	Link
n/a	Bladder cancer	EGFR, FGFR3	16	Link
	Leukemia	ABL1, JAK2	7	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, MET	19	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	4	Link
	Apert syndrome	FGFR2	4	Link
n/a	Multiple myeloma	FGFR3	5	Link
n/a	Pathogenic Escherichia coli infection	ABL1	6	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	5	Link
	Bent bone dysplasia syndrome	FGFR2	4	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	4	Link
	Scaphocephaly	FGFR2	4	Link
n/a	Saethre-Chotzen syndrome	FGFR2	4	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	4	Link
	Craniosynostosis	FGFR2	4	Link
n/a	Agammaglobulinemias	BTK	1	Link
n/a	Shigellosis	ABL1	6	Link
	Agammaglobulinemia	BTK	1	Link
	Adenocarcinoma of lung	EGFR	13	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	1	Link
n/a	Laryngeal cancer	EGFR	13	Link
n/a	Oral cancer	EGFR	13	Link
n/a	Esophageal cancer	EGFR	13	Link
n/a	Glioma	EGFR	13	Link
	Hypogonadotropic hypogonadism	FGFR1	8	Link
	Osteoglophonic dysplasia	FGFR1	8	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	6	Link
n/a	Viral myocarditis	ABL1	6	Link
n/a	Pituitary Dwarfism	BTK	1	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	4	Link
	Trigonocephaly	FGFR1	8	Link
n/a	CATSHL syndrome	FGFR3	5	Link
	Kallmann syndrome	FGFR1	8	Link
n/a	Nevus	FGFR3	5	Link
n/a	Achondroplasia	FGFR3	5	Link
n/a	Myasthenic syndrome	MUSK	2	Link
n/a	Alcoholism	NTRK2	6	Link
n/a	Obesity	NTRK2	6	Link
n/a	Congenital myasthenic syndrome	MUSK	2	Link
	Hepatocellular carcinoma	MET	8	Link
	Renal cell carcinoma	MET	8	Link
n/a	Cholangiocarcinoma	MET	8	Link
n/a	Malaria	MET	8	Link
n/a	Autism suseptibility	MET	8	Link
n/a	Amoebiasis	PTK2	5	Link
n/a	Thyroid cancer	RET	7	Link
	Pheochromocytoma	RET	7	Link
	Renal agenesis	RET	7	Link
n/a	Popliteal pterygium syndrome	RIPK4	2	Link
	Multiple endocrine neoplasia	RET	7	Link
n/a	Medullary thyroid carcinoma	RET	7	Link
n/a	Renal agenesis and Renal adysplasia	RET	7	Link
	Hirschsprung disease	RET	7	Link
n/a	Congenital central hypoventilation syndrome	RET	7	Link
	Central hypoventilation syndrome	RET	7	Link
	SCID	JAK3	5	Link
n/a	Immunodeficiencies	JAK3	5	Link
n/a	Lymphedemas	FLT4	5	Link
n/a	Lymphedema	FLT4	5	Link
n/a	Leprechaunism	INSR	4	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Thanatophoric dysplasia	FGFR3	5	Link
	Colorectal cancer	FGFR3	5	Link
n/a	Hypochondroplasia	FGFR3	5	Link
n/a	Muenke syndrome	FGFR3	5	Link
n/a	Spermatocytic seminoma	FGFR3	5	Link
	Rabson-Mendenhall syndrome	INSR	4	Link
	Diabetes mellitus	INSR	4	Link
	Myelofibrosis	JAK2	4	Link
n/a	Myeloproliferative disorder	JAK2	4	Link
	Thrombocythemia	JAK2	4	Link
n/a	Budd-Chiari syndrome	JAK2	4	Link
	Polycythemia vera	JAK2	4	Link
	Hyperinsulinemic hypoglycemia	INSR	4	Link
n/a	Invasive pneumococcal disease	IRAK4	4	Link
	IRAK4 deficiency	IRAK4	4	Link
	Lymphoproliferative syndrome	ITK	4	Link

BioXGEM.

KIDFamMap

Allelic Variants