KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2XB7A_GUI (PDB code: 2XB7, chain A)
Number of involved diseases in the family	107
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Measles	FYN, JAK1, JAK2, JAK3, MAP3K7, TYK2	2	Link
	Prostate cancer	EGFR, EPHB2, FGFR1, FGFR2, IGF1R, INSRR	38	Link
n/a	Epstein-Barr virus infection	FGR, JAK1, JAK3, MAP3K7, SYK, TYK2	2	Link
n/a	Tuberculosis	JAK1, JAK2, SRC, SYK	2	Link
	Melanoma	EGFR, FGFR1, IGF1R, MET	39	Link
n/a	Herpes simplex infection	JAK1, JAK2, MAP3K7, TYK2	2	Link
n/a	Toxoplasmosis	JAK1, JAK2, MAP3K7, TYK2	2	Link
	Lung cancer	ALK, EGFR, PTK2, ROS1	10	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, MET, SRC	3	Link
n/a	Hepatitis C	EGFR, JAK1, TYK2	2	Link
	Leukemia	ABL1, ABL2, JAK2	2	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	2	Link
	Gastric cancer	EGFR, FGFR2, MET	3	Link
n/a	Leishmaniasis	JAK1, JAK2, MAP3K7	2	Link
	Neuroblastoma	ALK, NTRK1, NTRK2	10	Link
n/a	Influenza A	JAK1, JAK2, TYK2	2	Link
n/a	Cervical cancer	EGFR, FGFR3	1	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	2	Link
	Hemangioma	FLT4, KDR	2	Link
n/a	Immunodeficiencies	JAK3, ZAP70	20	Link
n/a	Bladder cancer	EGFR, FGFR3	1	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	2	Link
n/a	Shigellosis	ABL1, SRC	2	Link
	Colon cancer	AURKA, SRC	2	Link
	Pfeiffer syndrome	FGFR1, FGFR2	2	Link
n/a	Choriocarcinoma	CSF1R, EGFR	1	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	2	Link
	LADD syndrome	FGFR2, FGFR3	1	Link
	Crouzon syndrome	FGFR2, FGFR3	1	Link
n/a	Thyroid cancer	NTRK1, RET	2	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	1	Link
	Apert syndrome	FGFR2	1	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	1	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	1	Link
n/a	Multiple myeloma	FGFR3	1	Link
n/a	Saethre-Chotzen syndrome	FGFR2	1	Link
	Craniosynostosis	FGFR2	1	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	1	Link
	Scaphocephaly	FGFR2	1	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	1	Link
	Bent bone dysplasia syndrome	FGFR2	1	Link
	Cataract	EPHA2	1	Link
	Kallmann syndrome	FGFR1	2	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	1	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	1	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	1	Link
	Agammaglobulinemia	BTK	1	Link
n/a	Maturity onset diabetes of the young	BLK	1	Link
n/a	Agammaglobulinemias	BTK	1	Link
n/a	Pituitary Dwarfism	BTK	1	Link
n/a	Oral cancer	EGFR	1	Link
n/a	Esophageal cancer	EGFR	1	Link
	Osteoglophonic dysplasia	FGFR1	2	Link
	Trigonocephaly	FGFR1	2	Link
	Hypogonadotropic hypogonadism	FGFR1	2	Link
n/a	CATSHL syndrome	FGFR3	1	Link
n/a	Glioma	EGFR	1	Link
n/a	Laryngeal cancer	EGFR	1	Link
	Adenocarcinoma of lung	EGFR	1	Link
n/a	Spermatocytic seminoma	FGFR3	1	Link
n/a	Achondroplasia	FGFR3	1	Link
n/a	Congenital myasthenic syndrome	MUSK	1	Link
n/a	Myasthenic syndrome	MUSK	1	Link
n/a	Insensitivity to pain	NTRK1	1	Link
n/a	Alcoholism	NTRK2	2	Link
	Hepatocellular carcinoma	MET	3	Link
n/a	Autism suseptibility	MET	3	Link
	Retinitis pigmentosa	MERTK	1	Link
	Renal cell carcinoma	MET	3	Link
n/a	Cholangiocarcinoma	MET	3	Link
n/a	Malaria	MET	3	Link
n/a	Obesity	NTRK2	2	Link
n/a	Amoebiasis	PTK2	1	Link
	Renal agenesis	RET	2	Link
n/a	Transient erythroblastopenia of childhood	TEC	1	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	2	Link
	Selective T-cell defect	ZAP70	20	Link
	Pheochromocytoma	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
n/a	46XY sex reversal 6	MAP3K1	1	Link
	SCID	JAK3	1	Link
n/a	Lymphedemas	FLT4	1	Link
n/a	Lymphedema	FLT4	1	Link
n/a	Prion diseases	FYN	1	Link
n/a	Malignant pleural mesothelioma	IGF1R	37	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Thanatophoric dysplasia	FGFR3	1	Link
	Colorectal cancer	FGFR3	1	Link
n/a	Hypochondroplasia	FGFR3	1	Link
n/a	Muenke syndrome	FGFR3	1	Link
n/a	Nevus	FGFR3	1	Link
n/a	Synovial sarcoma	IGF1R	37	Link
	Insulin-like growth factor I	IGF1R	37	Link
n/a	Budd-Chiari syndrome	JAK2	2	Link
	Myelofibrosis	JAK2	2	Link
n/a	Myeloproliferative disorder	JAK2	2	Link
	Thrombocythemia	JAK2	2	Link
	Polycythemia vera	JAK2	2	Link
	Lymphoproliferative syndrome	ITK	1	Link
n/a	Leprechaunism	INSR	11	Link
	Rabson-Mendenhall syndrome	INSR	11	Link
	Diabetes mellitus	INSR	11	Link
	Hyperinsulinemic hypoglycemia	INSR	11	Link

BioXGEM.

KIDFamMap

Allelic Variants