KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2XYNA_VX6 (PDB code: 2XYN, chain A)
Number of involved diseases in the family	105
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	CDC2, CDK2, FGR, JAK3, LYN, MAPK14, RIPK1, SYK	19	Link
	Leukemia	ABL1, ABL2, JAK2, KIT, PDGFRB, TGFBR1	17	Link
n/a	Measles	CDK2, FYN, IRAK4, JAK2, JAK3, PRKCQ	34	Link
	Prostate cancer	CDK2, EPHB2, FGFR1, FGFR2, PDGFRA, PDGFRB	13	Link
n/a	Tuberculosis	IRAK4, JAK2, MAPK14, SRC, SYK	27	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, LYN, MAPK14, SRC	15	Link
n/a	Leishmaniasis	IRAK4, JAK2, MAPK14	16	Link
n/a	Toxoplasmosis	IRAK4, JAK2, MAPK14	16	Link
n/a	Influenza A	IRAK4, JAK2, MAPK14	16	Link
n/a	Chagas disease	IRAK4, MAPK14, TGFBR1	3	Link
	Melanoma	FGFR1, PDGFRA, PDGFRB	2	Link
n/a	Herpes simplex infection	CDC2, CDK2, JAK2	25	Link
n/a	Salmonella infection	MAPK14, PKN1, PKN2	4	Link
	Lung cancer	ALK, CDK2, ROS1	14	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	5	Link
n/a	Shigellosis	ABL1, MAPK14, SRC	17	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	14	Link
	LADD syndrome	FGFR2, FGFR3	2	Link
n/a	Immunodeficiencies	JAK3, LCK	9	Link
n/a	Type I diabetes mellitus	ERBB3, PRKCQ	10	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	3	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	5	Link
	Crouzon syndrome	FGFR2, FGFR3	2	Link
n/a	Pertussis	IRAK4, MAPK14	3	Link
	SCID	JAK3, LCK	9	Link
	Colon cancer	AURKA, SRC	71	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	2	Link
n/a	Glioma	PDGFRA, PDGFRB	2	Link
n/a	Cardiomyopathy	PRKAA1, PRKAA2	2	Link
n/a	Hepatitis C	MAPK14, RIPK1	4	Link
	Pfeiffer syndrome	FGFR1, FGFR2	2	Link
	Kallmann syndrome	FGFR1	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	2	Link
	Apert syndrome	FGFR2	2	Link
	Gastric cancer	FGFR2	2	Link
	Bent bone dysplasia syndrome	FGFR2	2	Link
	Craniosynostosis	FGFR2	2	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	2	Link
	Trigonocephaly	FGFR1	2	Link
	Osteoglophonic dysplasia	FGFR1	2	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	2	Link
n/a	Epileptic encephalopathy	CDKL5	1	Link
	Hypogonadotropic hypogonadism	FGFR1	2	Link
n/a	Agammaglobulinemias	BTK	2	Link
n/a	Pituitary Dwarfism	BTK	2	Link
n/a	Chrondrodysplasia	BMPR1B	1	Link
	Brachydactyly	BMPR1B	1	Link
	Fibrodysplasia ossificans progressiva	ACVR1	2	Link
	Neuroblastoma	ALK	2	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
	Agammaglobulinemia	BTK	2	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	2	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	2	Link
n/a	Lethal congenital contractural syndrome	ERBB3	1	Link
n/a	Choriocarcinoma	CSF1R	2	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Cocaine addiction	CDK5	1	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
n/a	Early infantile epileptic encephalopathy	CDKL5	1	Link
n/a	Achondroplasia	FGFR3	2	Link
n/a	Saethre-Chotzen syndrome	FGFR2	2	Link
n/a	Thyroid cancer	RET	3	Link
n/a	Renal agenesis and Renal adysplasia	RET	3	Link
	Hirschsprung disease	RET	3	Link
	Diabetes mellitus	PRKCD	9	Link
n/a	Hypereosinophilic syndrome	PDGFRA	2	Link
n/a	Germ cell tumors	KIT	3	Link
	Mast cell leukemia	KIT	3	Link
	Mastocytosis with associated hematologic disorder	KIT	3	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	2	Link
n/a	Congenital central hypoventilation syndrome	RET	3	Link
	Central hypoventilation syndrome	RET	3	Link
n/a	Rheumatoid arthritis	TEK	3	Link
	Loeys-Dietz syndrome	TGFBR1	1	Link
n/a	Familial thoracic aortic aneurysm and dissection	TGFBR1	1	Link
	Multiple self-healing squamous epithelioma	TGFBR1	1	Link
	Venous malformations	TEK	3	Link
n/a	Transient erythroblastopenia of childhood	TEC	1	Link
n/a	Medullary thyroid carcinoma	RET	3	Link
	Multiple endocrine neoplasia	RET	3	Link
	Pheochromocytoma	RET	3	Link
	Renal agenesis	RET	3	Link
	Piebaldism	KIT	3	Link
	Thrombocythemia	JAK2	14	Link
n/a	Cervical cancer	FGFR3	2	Link
	Colorectal cancer	FGFR3	2	Link
n/a	Hypochondroplasia	FGFR3	2	Link
n/a	CATSHL syndrome	FGFR3	2	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	2	Link
	Scaphocephaly	FGFR2	2	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	2	Link
n/a	Multiple myeloma	FGFR3	2	Link
n/a	Bladder cancer	FGFR3	2	Link
n/a	Muenke syndrome	FGFR3	2	Link
n/a	Nevus	FGFR3	2	Link
	Lymphoproliferative syndrome	ITK	2	Link
	Polycythemia vera	JAK2	14	Link
n/a	Budd-Chiari syndrome	JAK2	14	Link
	Myelofibrosis	JAK2	14	Link
	IRAK4 deficiency	IRAK4	1	Link
n/a	Invasive pneumococcal disease	IRAK4	1	Link
n/a	Spermatocytic seminoma	FGFR3	2	Link
n/a	Thanatophoric dysplasia	FGFR3	2	Link
n/a	Cancer progression/metastasis	FGFR4	2	Link
n/a	Prion diseases	FYN	2	Link

BioXGEM.

KIDFamMap

Allelic Variants