KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3A4OX_STU (PDB code: 3A4O, chain X)
Number of involved diseases in the family	88
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	CDK2, EGFR, EPHB2, FGFR1, FGFR2, PDGFRA, PDGFRB, PDPK1	44	Link
n/a	Epstein-Barr virus infection	CDC2, CDK2, FGR, LYN, MAPK14, SYK	15	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, MAPK14, SRC	41	Link
	Leukemia	ABL1, ABL2, JAK2, KIT, PDGFRB	15	Link
	Melanoma	EGFR, FGFR1, PDGFRA, PDGFRB	41	Link
n/a	Tuberculosis	JAK2, MAPK14, SRC, SYK	21	Link
n/a	Bladder cancer	DAPK1, EGFR, FGFR3	39	Link
n/a	Measles	CDK2, FYN, JAK2	14	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	41	Link
n/a	Herpes simplex infection	CDC2, CDK2, JAK2	14	Link
	Lung cancer	CDK2, EGFR, PTK2	42	Link
n/a	Influenza A	JAK2, MAPK14, PRKCA	59	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA	61	Link
n/a	Shigellosis	ABL1, MAPK14, SRC	20	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
n/a	Cervical cancer	EGFR, FGFR3	38	Link
n/a	Salmonella infection	MAPK14, PKN1	12	Link
n/a	Leishmaniasis	JAK2, MAPK14	11	Link
n/a	Hepatitis C	EGFR, MAPK14	39	Link
n/a	Toxoplasmosis	JAK2, MAPK14	11	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	Gastric cancer	EGFR, FGFR2	39	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	12	Link
n/a	Choriocarcinoma	CSF1R, EGFR	43	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	12	Link
n/a	Immunodeficiencies	LCK, ZAP70	11	Link
n/a	Amoebiasis	PRKCA, PTK2	57	Link
	Kallmann syndrome	FGFR1	9	Link
n/a	Pituitary Dwarfism	BTK	5	Link
n/a	Agammaglobulinemias	BTK	5	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
	Trigonocephaly	FGFR1	9	Link
	Apert syndrome	FGFR2	8	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
	Agammaglobulinemia	BTK	5	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
n/a	Oral cancer	EGFR	38	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
	Fibrodysplasia ossificans progressiva	ACVR1	3	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	13	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
	Adenocarcinoma of lung	EGFR	38	Link
n/a	Cocaine addiction	CDK5	5	Link
n/a	Laryngeal cancer	EGFR	38	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	SCID	LCK	11	Link
	REtinitis pigmentosa	MAK	1	Link
	Mastocytosis with associated hematologic disorder	KIT	12	Link
	Mast cell leukemia	KIT	12	Link
	Thrombocythemia	JAK2	10	Link
	Piebaldism	KIT	12	Link
n/a	Germ cell tumors	KIT	12	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	1	Link
n/a	Pertussis	MAPK14	1	Link
	Diabetes mellitus	PRKCE	11	Link
	Colon cancer	SRC	19	Link
	Selective T-cell defect	ZAP70	10	Link
n/a	Pituitary tumor	PRKCA	55	Link
n/a	African trypanosomiasis	PRKCA	55	Link
n/a	Chagas disease	MAPK14	1	Link
n/a	Hypereosinophilic syndrome	PDGFRA	10	Link
n/a	Vibrio cholerae infection	PRKCA	55	Link
	Myelofibrosis	JAK2	10	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
n/a	Achondroplasia	FGFR3	7	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
	Craniosynostosis	FGFR2	8	Link
	Scaphocephaly	FGFR2	8	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	Prion diseases	FYN	10	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link
	Polycythemia vera	JAK2	10	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Nevus	FGFR3	7	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link

BioXGEM.

KIDFamMap

Allelic Variants