KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3CKXA_STU (PDB code: 3CKX, chain A)
Number of involved diseases in the family	141
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	CDC2, CDK2, EIF2AK2, EIF2AK4, FGR, JAK1, JAK3, MAP2K3, MAP2K6, MAP3K14, MAPK12, MAPK13, MAPK14, SYK, TBK1	20	Link
n/a	Influenza A	EIF2AK2, EIF2AK4, IRAK4, JAK1, JAK2, MAP2K1, MAP2K3, MAP2K6, MAPK1, MAPK12, MAPK13, MAPK14, PRKCA, RAF1, TBK1	61	Link
n/a	Tuberculosis	CAMK2A, CAMK2B, IRAK4, JAK1, JAK2, MAPK1, MAPK12, MAPK13, MAPK14, PLK3, RAF1, SRC, SYK	21	Link
	Prostate cancer	CDK2, CHEK2, EGFR, EPHB2, FGFR1, FGFR2, IGF1R, INSRR, MAP2K1, MAPK1, PDPK1, RAF1	46	Link
n/a	Measles	CDK2, CDK4, CDK6, EIF2AK2, EIF2AK4, FYN, IRAK4, JAK1, JAK2, JAK3, PRKCQ, TBK1	19	Link
	Leukemia	ABL1, ABL2, CDK4, CDK6, JAK2, MAP2K1, MAPK1, PIM1, RAF1, RPS6KB1, RPS6KB2	15	Link
n/a	Hepatitis C	EGFR, EIF2AK2, EIF2AK4, JAK1, MAPK1, MAPK12, MAPK13, MAPK14, RAF1, TBK1	42	Link
n/a	Toxoplasmosis	IRAK4, JAK1, JAK2, MAP2K3, MAP2K6, MAPK1, MAPK12, MAPK13, MAPK14	13	Link
	Melanoma	CDK4, CDK6, EGFR, FGFR1, IGF1R, MAP2K1, MAPK1, MET, RAF1	43	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, MAP3K14, MAPK12, MAPK13, MAPK14, MET, PAK1, SRC	42	Link
	Lung cancer	ALK, CDK2, CDK4, CDK6, EGFR, MAP3K8, PTK2, ROS1	43	Link
n/a	Herpes simplex infection	CDC2, CDK2, EIF2AK2, EIF2AK4, JAK1, JAK2, TBK1	15	Link
n/a	Alcoholism	CAMK4, CAMKK1, CAMKK2, MAP2K1, MAPK1, NTRK2, RAF1	12	Link
n/a	Leishmaniasis	IRAK4, JAK1, JAK2, MAPK1, MAPK12, MAPK13, MAPK14	12	Link
n/a	Shigellosis	ABL1, MAPK1, MAPK12, MAPK13, MAPK14, SRC	20	Link
n/a	Salmonella infection	MAPK1, MAPK12, MAPK13, MAPK14, PKN1, PKN2	13	Link
n/a	Chagas disease	IRAK4, MAPK1, MAPK12, MAPK13, MAPK14	6	Link
	Diabetes mellitus	INSR, MAPK1, PRKCD, PRKCE, PRKCZ	15	Link
n/a	Pertussis	IRAK4, MAPK1, MAPK12, MAPK13, MAPK14	6	Link
n/a	Amyotrophic lateral sclerosis	MAP2K3, MAP2K6, MAPK12, MAPK13, MAPK14	11	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	16	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA	61	Link
n/a	Cervical cancer	CDK4, EGFR, FGFR3	40	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
n/a	Immunodeficiencies	JAK3, LCK, ZAP70	16	Link
	Gastric cancer	EGFR, FGFR2, MET	39	Link
n/a	Prion diseases	FYN, MAP2K1, MAPK1	11	Link
n/a	Bladder cancer	DAPK1, EGFR, FGFR3	39	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	SCID	JAK3, LCK	16	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
n/a	Thyroid cancer	NTRK1, RET	18	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	18	Link
	Mental retardation	CASK, PAK3	8	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
	Colon cancer	AURKA, SRC	19	Link
n/a	Amoebiasis	PRKCA, PTK2	57	Link
n/a	Glioma	CDK4, EGFR	40	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
	Scaphocephaly	FGFR2	8	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
	Kallmann syndrome	FGFR1	9	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	Trigonocephaly	FGFR1	9	Link
	Craniosynostosis	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
	Osteosarcoma	CHEK2	5	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
	Agammaglobulinemia	BTK	5	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
n/a	FG syndrome	CASK	1	Link
n/a	Malignant melanoma	CDK4	6	Link
n/a	Pituitary Dwarfism	BTK	5	Link
n/a	Agammaglobulinemias	BTK	5	Link
	Fibrodysplasia ossificans progressiva	ACVR1	3	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
n/a	Juvenile polyposis syndrome	BMPR1A	2	Link
n/a	Polyposis	BMPR1A	2	Link
n/a	Cocaine addiction	CDK5	5	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Choriocarcinoma	EGFR	38	Link
n/a	Laryngeal cancer	EGFR	38	Link
	Adenocarcinoma of lung	EGFR	38	Link
n/a	Oral cancer	EGFR	38	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	Early infantile epileptic encephalopathy	CDKL5	1	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Epileptic encephalopathy	CDKL5	1	Link
	Breast cancer	CHEK2	5	Link
	Li-Fraumeni syndrome	CHEK2	5	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
n/a	Glycogen storage diseases	PHKG2	9	Link
n/a	Non-syndromic X-linked mental retardation	PAK3	8	Link
n/a	Cirrhosis due to liver phosphorylase kinase deficiency	PHKG2	9	Link
	Glycogen storage disease	PHKG2	9	Link
n/a	African trypanosomiasis	PRKCA	55	Link
n/a	Vibrio cholerae infection	PRKCA	55	Link
n/a	Obesity	NTRK2	9	Link
n/a	Insensitivity to pain	NTRK1	15	Link
	Hepatocellular carcinoma	MET	8	Link
n/a	Autism suseptibility	MET	8	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
n/a	Myasthenic syndrome	MUSK	5	Link
	Deafness	MYO3A	2	Link
n/a	Deafness, autosomal recessive	MYO3A	2	Link
n/a	Pituitary tumor	PRKCA	55	Link
n/a	Type I diabetes mellitus	PRKCQ	8	Link
n/a	Basal cell carcinoma	STK36	3	Link
	Renal agenesis	RET	11	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Venous malformations	TEK	32	Link
	Selective T-cell defect	ZAP70	10	Link
n/a	Rheumatoid arthritis	TEK	32	Link
	Pheochromocytoma	RET	11	Link
	Multiple endocrine neoplasia	RET	11	Link
	Noonan syndrome	RAF1	2	Link
	LEOPARD syndrome	RAF1	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	11	Link
	Hirschsprung disease	RET	11	Link
	Central hypoventilation syndrome	RET	11	Link
n/a	Congenital central hypoventilation syndrome	RET	11	Link
n/a	Malaria	MET	8	Link
n/a	Cholangiocarcinoma	MET	8	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link
n/a	Oguchi disease	GRK1	4	Link
n/a	Malignant pleural mesothelioma	IGF1R	5	Link
n/a	Synovial sarcoma	IGF1R	5	Link
n/a	Leprechaunism	INSR	5	Link
	Insulin-like growth factor I	IGF1R	5	Link
n/a	Congenital stationary night blindness	GRK1	4	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Achondroplasia	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Nevus	FGFR3	7	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
n/a	Parkinson disease	LRRK2	5	Link
n/a	Lewy body dementia	LRRK2	5	Link
	REtinitis pigmentosa	MAK	1	Link
n/a	Noonan syndrome and related disorders	MAP2K1	4	Link
	Renal cell carcinoma	MET	8	Link
	Cardiofaciocutaneous syndrome	MAP2K1	4	Link
	Thrombocythemia	JAK2	10	Link
n/a	Myeloproliferative disorder	JAK2	10	Link
	IRAK4 deficiency	IRAK4	4	Link
n/a	Invasive pneumococcal disease	IRAK4	4	Link
	Lymphoproliferative syndrome	ITK	6	Link
	Polycythemia vera	JAK2	10	Link
	Myelofibrosis	JAK2	10	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link

BioXGEM.

KIDFamMap

Allelic Variants